Main description:

This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.

Contents:

Chapter 1_Genomic Classification of Human Pathogens. -Chapter 2_Metagenomics of Human Microbiome. -Chapter 3_Genomic Landscape of Novel Coronavirus (2019-Ncov) Towards Better Diagnosis and Efficient Antiviral Therapies. -Chapter 4_Deciphering the Role of Epigenetic Reprogramming In Host-Pathogen Interactions. -Chapter 5_Applications of Next Generation Sequencing In Infectious Pathogens. -Chapter 6_Bioinformatics Applications in Human Pathogens. -Chapter 7_ Non-Coding RNA Profiling: Potential Application in Infectious Diseases. -Chapter 8_ Microarrays: A Road Map to Uncover Host Pathogen Interactions. -Chapter 9_RNA Sequencing as Strategy to Understand Pathogenesis. -Chapter 10_ Non-Coding RNA as Drug Target against Infectious Diseases. -Chapter 11_ Emerging Transcriptional Approach for Identification of Drug Targets in Human Pathogens. -Chapter 12_ Proteogenomics Applications in Human Pathogens.-Chapter 13_Proteomic Strategies for Understanding Host Pathogen Interactions.-Chapter 14_Antimicrobial and Therapeutic Peptides. -Chapter 15_ Structural Proteomics Guided Design of Antimicrobial Drugs and Vaccines. -Chapter 16_Mechanism of Action of Antimicrobial Agents against Clinically Important Pathogens: A Proteomic Approach. -Chapter 17_Application of Lipidomics in Understanding Host Pathogen Interaction. -Chapter 18_Metabolomics: Advances and Applications In Human Pathogens. -Chapter 19_Host-Pathogen Interactions: Nature Inspired Sialic Acid Based Biointerface Materials. -Chapter 20_Nanoparticles as Therapeutic Nanocargos Affecting Epigenome of Microbial Biofilms. -Chapter 21_Challenges and Prospects in Omics Approach to Pathogens