Main description:

This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resource for researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.

Contents:

Primary Risk Factors: - Basic Principles of Molecular Pathophysiology and Etiology of Cardiovascular Dysorders.- Aging.- Gender.- Gene Polymorphisms and Signaling Defects.- Diet and nutrition to Prevent and Treat Cardiovascular Diseases.- Physical activity and Cardiovascular Diseases.- Alcohol.- Tobacco.- Socioeconomic Aspects of Cardiovascular Health.- Stress and Psychological Factors.- Secondary Risk Factors.- Hypertension and Vascular Dysfunction.- Obesity and Diabetes.- Hyper- and Dyslipoproteinemias.- Hyperuricemia.- Biomarkers.- Cardiovacular Events.- Ischemic Heart Disease.- Stroke.- Heart Failure.- Cardiac Arrhythmias.- Pulmonary Hypertension.- Peripheral Artery Disease.- Venous Thromboembolism.- Abdominal Aortic Aneurism.