Main description:

This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment.

Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa.

Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.

Contents:

Preface I. Embriology 1 Embryology of the skin2 Embryology of the heart
II. Genetic diseases 3 Epidermolysis bullosa4 Cutaneous Manifestations of Aortic Disease5 Tuberous Sclerosis Complex: Skin and Heart: Pivotal Common and Early Signs6 Incontinentia pigmenti7 The Heart in Neurofibromatosis8 Cardiocutaneous desmosomal disorders SEE II.2
III. Inflammatory diseases 9 Lupus erythematosus and other collagen diseases10 Vasculitis11 Behcet's Disease12 Kawasaki disease
IV. Infectious 13 COVID-19 14 Lyme disease15 Syphillis16 Viral conditions (varicella, congenital rubella)
V. Metabolic and endocrine diseases 17 Xanthomas and abnormalities of lipid metabolism and storage18 Diabetes mellitus19 Lysosomal Storage Disorders - Fabry Disease20 Mastocytosis
VI. Drug reaction 21 Cardiotoxic and skin rections inducing medication22 Cardiovascular side effects of skin diseases treating medication23 The importance of cardiac assessment in the era of biologic therapies for psoriasis
VII. Erythoroderma (ex. High output cardiac failure - erythroderma, etc) 24 Erythroderma and cardiac function
VIII. Miscellaneous 25 Disorders of fluid regulation26 Infantile hemangiomas and the heart27 Erdheim Chester disease28 Cardiac Implantable Device Related Complications
Index