Main description:

Antibiotics - Therapeutic Spectrum and Limitations provides up-to-date information about the variation in microbial infections, detailed toxicity considerations, rational uses, development of resistance, and their control, while also providing thorough insights into the comprehensive and up-to-date trends and therapeutic uses of antibiotics and mechanisms of action. The chapters in this book discuss important aspects of microbial infections, antibiotics with different mechanisms, and antibiotic resistance by leading experts around the globe. Furthermore, these chapters include an updated literature review of relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables, attractive figures, and more.

Contents:

Section I: Introduction 1. Introduction to antibiotic therapy

Section II: Microbial infection and antibiotics development 2. Bacterial infection: Types and pathophysiology 3. Antibiotics - Past, Present & Possibilities 4. Challenges in the development of antibiotics

Section III: Antibiotics and therapeutics 5. Beta lactum antibiotics 6. Aminoglycoside antibiotics 7. Broad Spectrum Antibiotics (Chloramphenicol and Tetracycline) 8. Macrolide antibiotics 9. Lincosamide and glycopeptide antibiotics 10. Antimicrobial Lipopeptides: Multifaceted Designs to Curb Antimicrobial Resistance 11. Antifungal Compounds: With Special Emphasis on Echinocandins, Polyenes, Heterocyclic Benzofurans 12. Antibiotics in the management of tuberculosis and cancer

Section IV: Toxicity and Antibiotic resistance 13. Toxicity consideration of antibiotics 14. Rational use of antibiotics- save antibiotics for future generations 15. Combined use of antibiotics 16. Antibiotic resistance - a global crisis 17. Traditional Medicine in the Management of Microbial Infection as Antimicrobials: Pros and Cons

Section V: Others 18. Quinolones as antimicrobial and anti-resistance agents 19. Herbal drugs as antibiotics 20. Paediatric and geriatric uses of antibiotics 21. Role of antibiotics in hospital acquired infections and community acquired infections 22. Adult sepsis as an emerging hospital acquired infection: challenges and solutions 23. Probiotics: A solution to the prevention of antimicrobial resistance 24. Role of modern drug delivery in antibiotic therapy 25. Antibiotic residues in food 26. Clinical trials, regulatory considerations and market overview of antibiotics