Main description:

Students trained in traditional exercise physiology have learned the basic concepts of energy but often don't fully understand human energy consumption at the molecular level. Biochemistry Primer for Exercise Science, Fourth Edition, provides an introduction to biochemistry that will give readers greater insight into the molecular aspects of human physical activity.

Reflecting the rapid development of the field, this classic text continues to present the essentials of biochemistry-molecular biology, basic chemistry, metabolism, and transcription regulation-in an easy-to-understand format. The fourth edition features the most recent research in exercise biochemistry plus new and revised content, including the following:

* All-new coverage of the control of biochemistry and biochemical and muscular adaptations to exercise and training via signaling pathways, an area of study that has received much attention in recent years

* Added information on the regulation of gene expression, which highlights the need for students to comprehend the basics of molecular biology

* Next Stage sections in each chapter, which lead students toward emerging areas of knowledge in the field by examining new or controversial areas of research

* An integration of the chapters on DNA, RNA, and the regulation of protein synthesis to provide a more focused and effective presentation of these key concepts

Biochemistry Primer for Exercise Science, Fourth Edition, combines information from nutrition, physiology, and biochemistry to provide a clear explanation of the working of metabolism and the human body's response to physical activity. Special elements throughout the text help to demystify this complex and dynamic field of study. Key points reinforce essential concepts and aid readers in relating them to sport and exercise. Chapter summaries outline important information to take away, and review questions with answers allow readers to test their knowledge of each chapter's content. A comprehensive glossary and the list of abbreviations found on the inside front and back covers help readers become familiar with commonly used biochemistry terms, and a reference list provides a starting point for exploring areas of interest in more detail.

With its combination of essential topics, new findings, and future directions in research, Biochemistry Primer for Exercise Science, Fourth Edition, is a perfect resource for anyone looking to build an understanding of exercise biochemistry. Both students and professionals alike will find the information they need to begin their exploration of this fascinating field of study.

Contents:

Part I: Proteins and Enzymes: The Basis of Biochemistry

Chapter 1: Amino Acids, Peptides, and Proteins

Nature of Amino Acids

Characteristics of Peptides

Structure of Proteins

Next Stage: Proteomics

Summary

Review Questions

Chapter 2: Enzymes

Enzymes as Catalysts

Rates of Enzymatic Reactions

Enzyme Cofactors

Classification of Enzymes

Protein Transporters

Oxidations and Reductions

Regulation of Enzyme Activity

Measurement of Enzyme Activity

Next Stage: Redox Regulation of the SERCA Pump in Vascular Physiology and Disease

Summary

Review Questions

Chapter 3: Gene Transcription and Protein Synthesis

DNA and RNA

Transcription

Posttranscriptional Modifications of RNA

Translation

Posttranslational Processing of Polypeptides

Protein Degradation

Regulation of Gene Expression in Exercise and Training

Next Stage: MicroRNAs and the Adaptive Response to Exercise Training

Summary

Review Questions

Part II: Metabolism: Regulation and Adaptation to Exercise and Training

Chapter 4: Energy Systems and Bioenergetics

Energy Requirements of Skeletal Muscle

Energy-Rich Phosphates

Energy Systems

Bioenergetics

Next Stage: Epigenetic Control of Skeletal Muscle Fiber Type and Metabolic Potential

Summary

Review Questions

Chapter 5: Oxidative Phosphorylation

Overview of Metabolism

Mitochondria

Citric Acid Cycle

Electron Transport Chain

Coupled Phosphorylation

Regulation of Oxidative Phosphorylation

Quantification of Redox Reactions

Oxidants and Antioxidants

Next Stage: Effects of Aging and Exercise Training on Muscle Mitochondria

Summary

Review Questions

Chapter 6: Carbohydrate and Related Metabolism

Carbohydrates

Cellular Uptake of Glucose

Phosphorylation of Glucose

Glycolysis

Glycogen Metabolism

Lactate Metabolism

Oxidation of Cytoplasmic NADH

Gluconeogenesis

Pentose Phosphate Pathway

Signaling Pathways

Next Stage: Carbohydrate, Exercise Performance, and Fatigue

Summary

Review Questions

Chapter 7: Lipid Metabolism

Types of Lipids

Fat Storage and Metabolism

Oxidation of Fatty Acids

Oxidation of Ketone Bodies

Synthesis of Fatty Acids

Fat as Fuel for Exercise

Metabolism During Exercise: Fat Versus Carbohydrate

Adipose Tissue as an Endocrine Tissue

Cholesterol

Next Stage: Exercise, 24-Hour Fat Oxidation, and Weight Loss

Summary

Review Questions

Chapter 8: Amino Acid and Protein Metabolism

Overview of Amino Acid Metabolism

Degradation of Amino Acids

Urea Cycle

Fate of Amino Acid Carbon Skeletons

Amino Acid Metabolism During Exercise

Additional Roles for Amino Acids

Next Stage: Effects of Diet and Exercise on Protein Degradation and Synthesis

Summary

Review Questions