Main description:

This book provides an in-depth and up-to-date review of the association between blood pressure disorders and diabetes mellitus. In addition, it discusses the specific role of hemodynamic alterations on the vasculature of various target organs (the retina, kidney, brain, and gravid uterus), topics that are infrequently considered and or acknowledged by clinicians.

Covering all aspects of the interaction between metabolic and hemodynamic factors, the book presents
the diverse perspectives of the contributing authors and extensive discussions of issues including diabetic kidney disease, diabetic hypertensive phenotypes and postural hypotension.

Contents:

I Introduction.- 1 Coexistence of Diabetes Mellitus and Hypertension.- II Epidemiological Aspects.- 2 BP disorders in diabetic children/adolescents.- 3 Hypertension and Type 2 Diabetes Mellitus.- 4 BP Disorders in Gestational Diabetes (Hypertension / Preeclampsia).- III Screening and Diagnostic Approaches in Diabetic Hypertensive Patients.- 5 Office / Out-of-Office Blood Pressure Measurements.- 6 Laboratory Indices / Bioimaging.- IV Pathophysiological Mechanisms.- 7 Genetics.- 8 Insulin and BP relationships.- 9 Mechanisms of Diabetic Nephropathy in Experimental Animals.- 10 Molecular Alterations in Diabetic Chronic Kidney Disease.- V Target Organ Damage in Diabetic Hypertensive Patient.- 11 Endothelial Dysfunction / Arterial Stiffness.- 12 Heart in Diabetic Hypertensive Patients.- 13 Cerebrovascular Structural Alterations.- 14 Diabetic Nephropathy in Type 1 Diabetes Mellitus.- 15 Diabetic Chronic Kidney Disease in Type 2 Diabetes Mellitus (Albuminuric/ Nonalbuminuric).- 16 Diabetic Retinopathy.- VI Strategies for Blood Pressure Control.- 17 Target Blood Pressure Values / Choice of Antihypertensive Drug Classes.- VII Benefits of Antihypertensive Treatment.- 18 Lifestyle modification.- 19 Blood Pressure Thresholds for Initiation of Drug Treatment / and Effect of Blood Pressure Reduction on Target Organs.- VIII Antihypertensive Drugs and Diabetes Mellitus: Special Problems.- 20 Adverse reactions associated with RAAS Blockers.- 21 Insulin Resistance and New Onset Diabetes Mellitus.- 22 Management of Hypertensive Diabetic Patient during Ramadan Fasting.- IX Other Therapeutic Modalities.- 23 Control of Blood Glucose and Cardiovascular Risk Profile.- X Hypotensive Disorders.- 24 Supine / Postural Hypotensive Blood Pressure Levels.