Published November, 2012
By Paul C. Barrow
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The various international regulatory requirements are explained in detail, in order that the reader may perform all of the necessary studies for the successful registration or marketing authorisation of a new pharmaceutical, industrial chemical, crop protection product or food additive.

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Published October, 2012
By Mark Wilks
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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PCR methods for the detection of microbial pathogens have made relatively little impact in diagnostic microbiology laboratories due to the common decision to use expensive commercially produced tests rather than the cheaper alternative of developing one's own tests or introducing tests developed by other workers.

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Published October, 2012
By Mostafa Z. Badr, Jihan Youssef and Jihan A. Youssef
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology but differ in function, tissue distribution and ligand specificity.

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Published October, 2012
By Brad Reisfeld and Arthur N. Mayeno
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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This resource features essential background, context, examples, useful tips, and an overview of current developments in the field. It includes cutting-edge methods and protocols as well as implementation advice from the experts.

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Published October, 2012
By Alioscka A. Sousa and Michael J. Kruhlak
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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This volume in the Methods in Molecular Biology(TM) series explores light microscopy techniques; electron microscopy; scanning probe techniques and complementary methods including soft x-ray tomography and secondary ion mass spectrometry.

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Published October, 2012
By Stanislav S. Rubakhin and Jonathan V. Sweedler
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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In Mass Spectrometry Imaging: Principles and Protocols, expert practitioners from academia, industry, and the clinic contribute cutting-edge protocols describing the application of MSI to investigations of analyte localization in a variety of specimens, from microorganisms to plant and animal tissues.

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Published October, 2012
By Graeme L. Conn
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The discovery of catalytic RNAs in the mid-1980s marked the beginning of a new era in RNA biology and an ever increasing appreciation of the diverse and critical roles played by this fascinating molecule.

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Published October, 2012
By Debra J. Taxman
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The discovery of RNA interference (RNAi) as a methodology for gene silencing has revolutionized biological research, providing an invaluable avenue for therapeutics, and small interfering RNA (siRNA) is the most common strategy utilized for enacting RNAi.

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Published October, 2012
By Jurgen Roth, Douglas J. Taatjes and Douglas Taatjes
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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With new chapters covering colocalization analysis of fluorescent probes, correlative light and electron microscopy, environmental scanning electron microscopy, light sheet microscopy, intravital microscopy, high throughput microscopy, and stereological techniques.

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Published September, 2012
By Brad Reisfeld and Arthur N. Mayeno
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

The final section is a compilation of the key elements and main approaches used in pharmacokinetic and pharmacodynamic modeling, including the modeling of absorption, compartment and non-compartmental modeling, physiologically based pharmacokinetic modeling, interspecies extrapolation, and population effects.

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