Published February, 2012
By Robert C. Elston, Jaya M. Satagopan and Shuying Sun
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating: 1.00
Availability: Available

Recent advances in genetics over the last quarter of a century, especially in molecular techniques, have dramatically reduced the cost of determining genetic markers and hence opened up a field of research that is increasingly helping to detect, prevent and/or cure many diseases that afflict humans.

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Published January, 2012
By Beth J. Shapiro, Michael Hofreiter and Beth Shapiro
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating: 1.00
Availability: Available

Research into ancient DNA began more than 25 years ago with the publication of short mitochondrial DNA sequence fragments from the quagga, an extinct relative of the zebra.

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Published January, 2012
By Firas H. Kobeissy and Firas Kobeissy
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
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Opening with a review of animal research in psychiatric illness and substance abuse, this book discusses modeling of neuropsychiatric illness, drug abuse paradigms and techniques, biomarker identification, autoimmune inflammatory response and other topics.

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Published January, 2012
By Lars Feuk
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
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Characterization of copy number variation and other forms of structural genetic variation has highlighted the complexity of human genetic variation and also provided significant insight into the evolution and dynamic nature of our genome.

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Published January, 2012
By Xu Peng and Marc Antonyak
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
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These include methods and technique for using different organisms for cardiovascular developmental research, using cell and molecular biology methods to study cardiovascular development, as well as other available techniques for cardiovascular development research.

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Published January, 2012
By Leslie W. Tari
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads.

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Published January, 2012
By Lee-Jun C. Wong
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The variability of clinical symptoms in mitochondrial diseases calls for a systematic presentation of the full range of protocols used in their assessment. This volume provides cutting-edge methods of analysis as well as expert guidance on how to apply them.

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Published December, 2011
By Peter E. Vaillancourt
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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coli vectors and strains for production of pure, functional protein, and the use of E. Among the cutting-edge techniques demonstrated are those for rapid high-level expression and purification of soluble and functional recombinant protein and those essential to functional genomics, proteomics, and protein engineering.

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Published December, 2011
By Chiquito J. Crasto and S.H. Koslow
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Neuroinformatics presents cutting-edge techniques for the synergistic study of neuroinformatics. The book facilitates the efforts of discovering neuroscience through the sharing of data and the use of computational models. It contains detailed explanations, advantages, and disadvantages of traditional and non-invasive imaging methods.

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Published December, 2011
By Tiziana Borsello
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
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This book examines current research into the role of neuronal death in cell signaling pathways, and its role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. After introducing neurodegenerative, traumatic, and ishemic disorders, the authors cover in vitro and animal systems, and cellular and molecular mechanisms.

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