Published July, 2011
By Graeme I. Murray
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Laser microdissection techniques have revolutionized the ability of researchers in general, and pathologists in particular, to carry out molecular analysis on specific types of normal and diseased cells and to fully utilize the power of current molecular technologies including PCR, microarrays, and proteomics.

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Published July, 2011
By John Goodchild
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This volume in the Methods in Molecular Biology(TM) series presents established and emerging methods for the application of oligonucleotides as therapeutics. Includes protocols for optimizing cell uptake, assaying gene knockdown, target site selection and more.

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Published July, 2011
By James A. Williams
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Classical methods for microbial strain engineering, used to improve the production of bioproducts, have serious drawbacks and have been found to be unsuitable for complex strain development applications.

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Published June, 2011
By Jonathan P. Rast and James W.D. Booth
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

These include imaging techniques that aim to understand receptor localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze downstream receptor signaling, as well as strategies for genomic and proteomic characterization of receptor repertoires.

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Published June, 2011
By Gary B. Willars and R.A. John Challiss
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

As our understanding of G protein-coupled receptor (GPCR) signal transduction continues to grow, we cannot help but be struck by the emerging complexity and the ability of this receptor superfamily to continually surprise us as new facets are discovered.

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Published June, 2011
By Sonny S. Mark
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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In this book, researchers update the classic methods and introduce new approaches that go beyond basic conjugation techniques. There is emphasis on the interplay of organic synthesis, molecular biology, surface biotechnology and biomaterials engineering.

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Published June, 2011
By Hideo Tsubouchi
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, and yeast genetics has successfully provided a framework for the mechanism of homologous recombination.

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Published May, 2011
By Jin-Rong Xu and Burton H. Bluhm
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Methods in Molecular Biology
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Fungal Genomics explores the three most likely fronts upon which the field will advance: the sequencing of more fungal genomes, the mining of sequenced genomes for useful information, and the use of genomics sequences to explain biological processes.

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Published May, 2011
By Jonathan M. Keith
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

In this book, leading researchers in the field of Bioinformatics provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems.

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Published May, 2011
By Mouldy Sioud
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

In this easy-to-use and up-to-date volume, expert researchers explore the most recent advances in siRNA design, expression, delivery, in vivo imaging, and methods. The aim is to minimize siRNA's unwanted effects and promote successful use in patients.

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