Published September, 2011
By Stephen B. Dunnett and Emma L. Lane
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

Here are techniques for modeling and assessing motor function in experimental animals from lower orders through vertebrates to mammals. Vol. II covers basal ganglia, neo- and allo-cortical systems, cerebellar and brain stem systems and spinal cord systems.

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Published September, 2011
By Todd D. Gould
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

Preclinical research related to mood and anxiety disorders relies extensively upon mouse behavioral tests and models, the use of which continues to increase as a greater number of underlying susceptibility genes are discovered, new targets for medications are identified, and clinical studies reveal novel neurobiological risk factors.

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Published June, 2011
By Patricio O'Donnell
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

Animal models of schizophrenia and other major psychiatric disorders have been sought for decades and we now face new vistas on pathophysiology. Covering the key areas of research, this book explores the use of animal models in this difficult area of study.

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Published May, 2011
By Ka Wan Li
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

This book offers detailed protocols in the growing area of neuroproteomics, with step-by-step, easy to follow instructions, practical tips and key implementation advice, along with established methods that play supporting roles in the workflow.

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Published May, 2011
By Scott Q. Harper
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

Non-coding, inhibitory microRNAs have emerged as important modulators of cellular gene expression, through a process called RNA interference (RNAi).

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Published March, 2011
By Michael Aschner, Cristina Sunol, Anna Bal-Price and Anna K. Bal-Price
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
Rating: 1.00
Availability: Available

Societal, ethical, and cost-related issues, not to mention the need for sound scientific methods, have led to new and refined methods for the evaluation of health risks associated with neurotoxic compounds, relevant and predictive of exposure, relatively inexpensive, and ideally amenable to high throughput analysis and a reduction in animal use.

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Published March, 2011
By James J. Chambers and Richard H. Kramer
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

This book provides an unbiased comparison of the various photochemical tools currently available for controlling neuronal activity in order to aid scientists in the vital goal of choosing the right tools for the job.

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Published December, 2010
By Mary C. Olmstead
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse.

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Published December, 2010
By Illana Gozes
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

As such, many techniques are required to understand the contribution and functions of neuropeptides in health and disease processes. Research in the neuropeptide field is aimed toward a better understanding of the physiology of the human body and toward the development of better diagnostics and therapeutics.

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Published December, 2010
By Peter Paul de Deyn and Debby van Dam
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Availability: Available

With an ever-increasing elderly population and the resultant rising levels of dementia-related disorders, preclinical research based on animal models is pivotal to our knowledge of underlying molecular mechanisms and drug discovery aiming at the development of therapeutic strategies alleviating or preventing the neurological devastation.

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