Published February, 2014
By Colm Duffy
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Springer Theses
Rating:
Availability: Available

In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Both routes have inspired further work in the synthesis of further heteroaromatic analogues for biological evaluation.

---

Published February, 2014
By Xiao-Yu Sun
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Springer Theses
Rating:
Availability: Available

In his thesis, Xiaoyu Sun conducts the first total synthesis of all possible stereoisomers of plakortide E and also confirms the absolute configuration of natural plakortide E.

---

Published February, 2014
By Zaozao Qiu
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Springer Theses
Rating:
Availability: Available

However, their unique structures make derivatization difficult and the limited efficient synthetic methods to obtain functional carborane materials have restricted applications of carboranes within a narrow scope.

---

Published January, 2014
By Zacarias Leon and Zacarias Leon Gonzalez
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
Rating:
Availability: Available

Zacarias Leon's thesis describes the development and validation of analytical methods to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products.

---

Published November, 2013
By Michael A. Colman
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
Rating:
Availability: Available

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality.

---

Published October, 2013
By Lina K. Blusch
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
Rating:
Availability: Available

This thesis describes the first and long-sought successful synthesis of a new pyrazole-expanded porphyrin, a higher analog of porphyrin. In her thesis, Lina Blusch not only explains the challenging synthesis and characterization of the ligand system, but also its application to the synthesis of homo- and hetero-bimetallic Ni and Cu complexes.

---

Published October, 2013
By Tsukasa Mizuhara
Publisher: Springer (Springer Verlag, Japan)
Series: Springer Theses
Rating:
Availability: Available

The author successfully developed novel anti-HIV PD 404182 derivatives that exhibited submicromolar inhibitory activity against both HIV-1 and HIV-2. The second part explains SAR studies of PD 404182 for the development of anti-HIV agents.

---

Published October, 2013
By Eva Maria Huber
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
Rating:
Availability: Available

In this acclaimed thesis, Eva Maria Huber reveals ground-breaking results by elucidating the crystal structure of the murine immunoproteasome in complex with a selective inhibitor.

---

Published July, 2013
By Janet T. F. Lau
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
Rating:
Availability: Available

Janet Lau's thesis describes her studies into the use of phthalocyanine-based photosensitizers in combined chemo- and photodynamic therapy (PDT) and targeted PDT.

---

Published June, 2013
By Yue Yanan
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
Rating:
Availability: Available

Furthermore, by using a combination of synthetic chemistry, polymer physics and molecular biology, Yue confirms that it is those cationic polymer chains free in the solution mixture, rather than those bound to DNA chains, that play a decisive role in intracellular trafficking.

---