Main description:

Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of 113Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted.

Feature:

Provides an up-to-date information on the role of cadmium in life

Covers the toxicology of cadmium including its effect on cancer

Describes the essentiality of cadmium for marine microorganisms

Describes the analytical tools needed for cadmium studies of biological samples

Describes the biogeochemistry of cadmium, its release into the environment and effects on plants

Back cover:

Cadmium: From Toxicity to Essentiality, MILS-11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of ¹¹³Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted. The book terminates with a fascinating report on the use of Cd(II) in carbonic anhydrase of certain marine phytoplankton species.

Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.

Contents:

1. The Bioinorganic Chemistry of Cadmium in the Context of Its Toxicity; Wolfgang Maret and Jean-Marc Moulis

2. Biogeochemistry of Cadmium and Its Release to the Environment; Jay T. Cullen and Maria T. Maldonado

3. Speciation of Cadmium in the Environment; Francesco Crea, Claudia Foti, Demetrio Milea, and Silvio Sammartano

4. Determination of Cadmium in Biological Samples; Katrin Klotz, Wobbeke Weistenhöfer, and Hans Drexler

5. Imaging and Sensing of Cadmium in Cells; Masayasu Taki

6. Use of ¹¹³Cd NMR to Probe the Native Metal Binding Sites in Metalloproteins: An Overview; Ian M. Armitage Torbjörn Drakenberg and Brian Reilly

7. Solid State Structures of Cadmium Complexes with Relevance for Biological Systems; Rosa Carballo, Alfonso Castiñeiras, Alicia Domínguez-Martín, Isabel García Santos and Juan Niclós-Gutierrez

8. Complex Formation of Cadmium(II) with Sugar Residues, Nucleobases, Phosphates, Nucleotides, and Nucleic Acids; Roland K. O. Sigel, Miriam Skilandat, Astrid Sigel, Bert P. Operschall and Helmut Sigel

9. Cadmium(II) Complexes of Amino Acids and Peptides; Imre Sóvágó and Katalin Várnagy

10. Natural and Artificial Proteins Containing Cadmium; Anna F. A. Peacock and Vincent L. Pecoraro

11. Cadmium in Metallothioneins; Eva Freisinger and Milan Vašák

12. Cadmium-Accumulating Plants; Hendrik Küpper and Barbara Leitenmaier

13. Cadmium Toxicity in Plants; Elisa Andresen and Hendrik Küpper

14. Toxicology of Cadmium and Its Damage to Mammalian Organs; Frank Thévenod and Wing-Kee Lee

15. Cadmium and Cancer; Andrea Hartwig

16. Cadmium in Marine Phytoplankton; Yan Xu and François M. M. Morel