Main description:

Provides the current state of the art of genome editing technologies used in basic and applied research.
Bring the latest advances in CRISPR/Cas9 technologies for treating genetic diseases.
Provides future prospects and directions for clinical research.

Contents:

1. The CRISPR/Cas9 Genome-editing System: Principles and Applications 2. Recent Applications of CRISPR-Cas9 in Genome Mapping and Sequencing 3. Gene Editing and Genetic Disorders: Ethical and Legal Concerns 4. Political, Regulatory and Ethical Considerations of the CRISPR/Cas Genome Editing Technology 5. CRISPR/Cas and Gene Therapy: An Overview 6. CRISPR and Cancer: From Bench to Clinic 7. The Advances of the CRISPR/Cas9 Technology for Correcting Genetic Disorders: Using Sarcoma as a Model System 8. CRISPR/Cas9 Technology as a Strategy Against Viral Infections 9. CRISPR/Cas9-based Genome and Epigenome Editing in Neuroscience Research 10. Non-viral Alternatives to Delivery of CRISPR-Cas Gene Editing Components 11. CRISPR Medicine: Advance, Progress and Challenges