Main description:

This book presents the latest information on the clinical-pathological features of diabetic kidney disease. The data included is based on a cohort study of biopsy-proven diabetic nephropathy patients and nephrosclerosis patients, who were observed over a long term, and on the long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan. It provides a clinical-pathological axis in clinical settings, including differential pathological/clinical diagnoses of CKD in diabetic patients (e.g. the presence of "classic" diabetic nephropathy and/or nephrosclerosis and/or other primary kidney diseases). The abundant biopsy specimens with long-term medical records provide a detailed pathological and clinical description. The book also includes urine-sample data for developing and validating possible candidates for novel biomarkers for diabetic kidney disease.Many countries, including Japan, have ageing populations, in which nephrosclerosis contributes to the progression of kidney lesions in patients with diabetic kidney disease. As such, a comparison of a diabetic nephropathy cohort with nephrosclerosis is indispensable to offer better treatments.This comprehensive and informative book is an indispensible reference resource for all physicians and researchers in the field of nephrology and diabetes.

Contents:

Part 1 Clinical aspectsChapter 1. Clinical epidemiology of diabetic kidney diseaseChapter 2. Long-term registry for diabetic nephropathy (diabetic kidney disease) in JapanChapter 3. CVD and diabetic kidney disease Chapter 4. Possible biomarkers for diabetic kidney diseaseChapter 5. Treatment of Diabetic kidney diseaseChapter 6. Future perspectives for treatment of diabetic kidney disease
Part 2. Pathological aspectsChapter 7. Type 1 and 2 diabetes and kidney pathologyChapter 8. Study at AMED collecting 711 biopsy-proven diabetic nephropathyChapter 9. Evaluation for diabetic kidney lesionsChapter 10. Nephrosclerosis and diabetic kidney diseasesChapter 11. Primary kidney diseases and diabetic kidney diseaseChapter 12. Experimental and human diabetic kidney lesions