Main description:

This book provides a comprehensive guide for selective venous sampling procedures and the role of interventional radiologists in the care and treatment of patients with endocrine disorders. Disorders of the endocrine system involve an imbalance in the natural homeostasis of the hormones produced by the glands in the body. There are a variety of endocrine conditions that are characterized by either hormonal hyposecretion or hypersecretion. Percutaneous selective venous sampling is the gold standard diagnostic tool for the medical and surgical management of patients with a variety of such disorders. Selective venous sampling is a minimally invasive interventional procedure that interventional radiologists perform to localize sites of abnormal hormone secretion. Computed tomography and magnetic resonance imaging are the most used diagnostic imaging modalities in patients with the suspected endocrine disorder; however, their specificity is not optimal, and identifying a culprit gland is difficult based on imaging findings alone. Therefore, the ultimate decision for management depends on the outcome of selective venous sampling. As these various venous samplings are increasingly performed worldwide, the collaboration between interventional radiology, endocrinology, surgical endocrinology, surgical oncology, neurosurgery, and gynecology teams is essential.

With limited literature on the topic, this volume fills the gap with in-depth coverage of selective venous sampling alongside the pathophysiology, epidemiology, clinical diagnosis, as well as medical, surgical, and interventional management of endocrine disorders. The book is divided into five parts: Clinical, Laboratory, and Radiological Diagnosis of Endocrine Disorders; Selective Venous Sampling in Interventional Radiology; Medical Treatment of Endocrine Disorders; Surgical Treatment of Endocrine Disorders; Interventional Treatment of Endocrine Disorders. Throughout these parts, endocrine disorders that require venous sampling are covered in depth: primary aldosteronism, primary hyperparathyroidism, Cushing's disease, hormone-secreting pancreatic adenomas, and androgen-secreting ovarian tumors. There is additionally an emerging role for interventional management in thyroid gland disorders, which is covered here.

This is an ideal guide for interventional radiologists caring for patients with endocrine disorders, as well as endocrinologists, endocrine surgeons, surgical oncologists, otolaryngologists, neurosurgeons, gynecologists, and nephrologists.

Contents:

PART 1. Clinical & Laboratory Diagnosis of Endocrine Disorders

Chapter 1. Clinical Evaluation

* Primary aldosteronism

* Hyperparathyroidism

* Hyperandrogenism (Hirsutism)

* Pancreatic islet cell tumors (insulinoma & gastrinoma)

* Cushing's disease (ACTH-producing pituitary tumor)

* References

Chapter 2. Laboratory Evaluation (Clinical Chemistry and Pathology)

* Primary aldosteronism

* Hyperparathyroidism

* Hyperandrogenism (Hirsutism)

* Pancreatic islet cell tumors (insulinoma & gastrinoma)

* Cushing's disease (ACTH-producing pituitary tumor)

* References

PART 2. Selective Venous Sampling in Interventional Radiology

Chapter 3. Primary Aldosteronism

* Introduction

* Indication

* Anatomy

* Procedure

* Results

* Complications

* References

Chapter 4. Hyperparathyroidism

* Introduction

* Indication

* Anatomy

* Procedure

* Results

* Complications

* References

Chapter 5. Hyperandrogenism (Hirsutism)

* Introduction

* Indication

* Anatomy

* Procedure

* Results

* Complications

* References

Chapter 6. Cushing's Disease (ACTH-producing Pituitary Adenoma)

* Introduction

* Indication

* Anatomy

* Procedure

* Results

* Complications

* References

Chapter 7. Pancreatic Islet tumors (Insulinoma & Gastrinoma)

* Introduction

* Indication

* Anatomy

* Procedure

* Results

* Complications

* References

PART 3: Medical Treatment of Endocrine Disorders

Chapter 8. Medical Treatment of Endocrine Disorders

* Primary aldosteronism

* Hyperparathyroidism

* Hyperandrogenism (Hirsutism)

* Pancreatic islet cell tumors (insulinoma & gastrinoma)

* Cushing's disease (ACTH-producing pituitary tumor)

* References

PART 4: Surgical Treatment of Endocrine Disorders

Chapter 9. Surgical Treatment of Primary aldosteronism

Chapter 10 Surgical Treatment of Hyperparathyroidism

Chapter 11. Surgical Treatment of Hyperandrogenism (Hirsutism)

Chapter 12. Surgical Treatment of Pancreatic islet cell tumors (insulinoma & gastrinoma)

Chapter 13. Surgical Treatment of Cushing's disease (ACTH-producing pituitary tumor)

PART 5: Interventional Treatment of Endocrine Disorders

Chapter 14. Interventional Treatment of Adrenal Adenoma with Primary Aldosteronism

* Thermal ablation

Chapter 15. Interventional Treatment of Parathyroid Adenoma with Primary Hyperparathyroidism

* Embolization

* Thermal ablation

Chapter 16. Interventional Treatment of Thyroid Nodule with Hyperthyroidism

* Thermal ablation

Chapter 17. Interventional Treatment of Pancreatic Islet Cell Transplantation

Chapter 18. Interventional Treatment of Hepatic Endocrine Tumor

* Thermal ablation

* Embolization