Main description:

This book is about the legal, economical, and practical assessment and management of risky activities arising from routine, catastrophic environmental and occupational exposures to hazardous agents. It includes a discussion of aspects of US and European Union law concerning risky activities, and then develops the economic analyses that are relevant to implementing choices within a supply and demand framework. The book also discusses exposure-response and time-series models used in assessing air and water pollution, as well as probabilistic cancer models, including toxicological compartmental, pharmaco-kinetic models and epidemiological relative risks and odds ratios-based models. Statistical methods to measure agreement, correlation and discordance are also developed. The methods and criteria of decision-analysis, including several measures of value of information (VOI) conclude the expositions. This book is an excellent text for students studying risk assessment and management.

Contents:

Chapter 1. Legal Principles, Uncertainty, and Variability In Risk Assessment and Management.-
Chapter 2. Sustainability and Making Decisions Under Uncertainty.-
Chapter 3. Risk, Cost, and Benefit Analysis (Rcba) In Risk Assessment and Management.
Chapter 4. Exposure-Response Models For Risk Assessment.-
Chapter 5. Probabilistic Dose-Response Models and Concepts of Toxicology.-
Chapter 6. Monte Carlo, Bootstraps and Other Methods to Quantify or Propagate Variability and Uncertainty.-
Chapter 7. Causal Models: Influence Diagrams, Bayesian Networks, Classification and Regression Trees.-
Chapter 8. Meta-Analysis, Pooling Sample Data, and Statistical Decision Rules.-
Chapter 9. Contingency Tables In Risk Assessment and Management.-
Chapter 10. Statistical Associations and Causation For Risk Assessment and Management.-
Chapter 11. Risk Assessment Frameworks, Calculations Of Risk and Toxicological Doses.-
Chapter 12. Practical Analysis Of Decisions For Risk Management.-
References. Glossary. List Of Symbols. Index.