Main description:

This book provides an overview of endocrine diseases associated with alterations of salt metabolism, with a focus on clinical and pathophysiological aspects. It covers various topics in the endocrine control of salt and water homeostasis, such as neuroendocrine determinants of water balance, adrenal hormone biosynthesis, hormonal function in target renal cells, and dysfunction of hormonal target effectors in the kidney. It also features an update on the clinical management of these diseases, including new diagnostic and therapeutic tools.

Written by a combination of recognized and emerging experts in the field, this book is intended as a major reference work, not only for endocrinologists and nephrologists, but also for pediatricians, neonatologists, cardiologists, and emergency medicine and intensive care specialists, who can be faced with the management of endocrine diseases responsible of salt and water imbalance.

The book is part of the SpringerReference program, which provides access to 'living editions' that are constantly updated using a dynamic, peer-review publishing process.

Contents:

Neuroendocrine Regulation of Hydro Saline Metabolism - Physiology of vasopressin secretion - Tubulopathies and Alterations of the RAAS - Familial Hyperkalemic Hypertension (FHHt) - Diabetes insipidus: Novel diagnostic approaches - SIADH - Hydro-Saline Alterations in Central Adrenal Insufficiency - Approach to Hyponatremia According to the Clinical Setting - Electrolyte disturbance in congenital adrenal hyperplasia due to 21-OH deficiency - Rare forms of congenital adrenal hyperplasia affecting electrolyte homeostasis - Apparent Mineralocorticoid Excess - Aldosterone resistance - Primary aldosteronism - MR and Aldosterone: From Hydro-Saline Metabolism to Metabolic Diseases - Hydrosaline Alterations in Cushing Disease