Main description:

Inflammatory Bowel Disease - Diagnostic and Therapeutic Strategies is the proceedings of the Falk Symposium 154 held in Moscow, Russia, on June 9–10 2006, and presents the most recent progress in our current understanding of the mechanisms of inflammatory bowel disease, the therapeutic state of the art, and future options of treatment.

The first half focuses on the role of the immune system, genetic factors, and intestinal microflora in IBD. The second half provides an evidence-based update on the current therapeutic options and presents future perspectives for the management of IBD. In particular, emphasis is placed on various so-called ‘biological’ therapies that are opening a whole new therapeutic era.

The authors and editors are a selected group of international experts, who contribute their wide experience of the mechanisms and management of IBD. Because of this, the book will be of equal interest to basic scientists and clinicians.

Feature:

Interdisciplinary symposium bringing together basic science and clinical applications

Up-to-date research findings at the highest scientific level

Contents:

From the Contents List of principal contributors List of chairpersons Preface SECTION I: MECHANISMS OF INFLAMMATORY BOWEL DISEASE: 1st SESSION.- 1 State-of-the-Art Lecture: The multifactorial pathogenesis of inflammatory bowel disease.- 2 CD1d: at the cusp of innate and adaptive immunity in regulating mucosal inflammation.- 3 Control of mucosal immune responses by transforming growth factor-beta.- 4 Immunoregulation: Crohn's disease versus ulcerative colitis.- 5 Role of Toll-like receptors in inflammatory bowel diseases.- 6 Animal models in inflammatory bowel disease.- 7 Epidemiology of inflammatory bowel disease in Russia.- SECTION II: MECHANISMS OF INFLAMMATORY BOWEL DISEASE: 2nd SESSION.- 8 State-of-the-Art Lecture: Genetics and genomics: implications for clinical practice.- 9 Genetic factors in the inflammatory bowel disease.- 10 Genotype-based classification of inflammatory bowel disease phenotype.- 11 Role of the intestinal barrier in inflammatory bowel disease.- SECTION III: MANAGEMENT OF INFLAMMATORY BOWEL DISEASE: 1st SESSION.- 12 Histological evaluation of activity of the ulcerative colitis in its initial stage of development.- 13 Crohn's disease of the small intestine: versions of clinical picture and problems of differential diagnosis.- 14 Distal colitis as a special pattern of ulcerative colitis.- 15 Implications of dysplasia in the prevention of ulcerative colitis-associated colo.- 16 The chemopreventive effect of aminosalicylates.- 17 The role of antibiotics and probiotics in Crohn's disease.- SECTION IV: MANAGEMENT OF INFLAMMATORY BOWEL DISEASE: 2nd SESSION.- 18 Indications for use of infliximab in inflammatory bowel disease.- 19 Therapy of inflammatory bowel disease: step-up or top-down.- 20 State of the Art Lecture: Emerging biologic therapies.- 21 Surgical treatment of complications of Crohn's disease.- 22 Surgical treatment of ulcerative colitis.- Index