Main description:

Introduction to Bioinformatics for Bacterial Genomics introduces bioinformatics techniques and programming using bacterial genomics as the main application area. This advanced-level text book introduces the student to both bioinformatics and bacterial genomics, with one topic motivating the other and vice versa. The strategy of this text is to lead the reader to a series of progressively more complex steps in the analysis of a bacterial genome, introducing new bioinformatics techniques at each step.
Introduction to Bioinformatics for Bacterial Genomics includes three classes of exercises: 1) theoretical exercises; 2) tool-development programming exercises; 3) genome analysis exercises. This book helps the student be as technology-independent as possible, concentrating on basic concepts, ideas, biological and mathematical problems, and techniques to solve them. After reading this text, the student will develop an essential "toolkit" for genome analysis. The results of applying this toolkit to a real genome is described in detail.

Feature:

First text book to present hands-on approach to teach bioinformatics using bacterial genomics as the platform

Includes algorithm design, algorithm implementation, and application on real data

Will help improve programming skills of life science students and introduce mathematical sciences students to genomics

Back cover:

Introduction to Bioinformatics for Bacterial Genomics is designed as an advanced-level text for students in computer science and biomedicine. This text is also suitable for practitioners and researchers in industry. Introduction to Bioinformatics for Bacterial Genomics will include access to a solution’s manual.

Contents:

Preface.- Introduction.- Step 1: Genome Bioinformatics Basics.- Step 2: Finding Protein-Coding Genes.- Step 3: Finding RNA Genes.- Step 4: Phylogeny.- Step 5: Gene Annotation.- Step 6: Comparative Genomics.- Odds and Ends.- Complete Genome Analysis.- Final Topics.- Bibliography/References.- Index.