Main description:

Isocoumarin, Thiaisocoumarin and Phosphaisocoumarin: Natural Occurrences, Synthetic Approaches and Pharmaceutical Applications gives an overview of the various aspects of this class of heterocycle, with a major focus on synthesis and biological activity. Aromatic d lactones or isocoumarins with thiaisocoumarins, phosphaisocoumarins and a-pyranone fused with a heteroaryl ring constitute an important class of heterocyclic compounds. This book provides the methods applied for the synthesis of thiaisocoumarins, phosphaisocoumarins, and a-pyranone fused with a heteroaryl ring. It is useful to medicinal and natural product chemists who want to synthesize target molecules and develop cutting-edge technologies to provide better solutions to researchers.

Contents:

1. Introduction: The diverse aromatic d lactones 2. Natural products: A major source of isocoumarins 3. Bioactive isocoumarins: their role in pharmaceutical research 4. Synthesis of isocoumarins: traditional and transition metal catalyzed methods 5. Preparation of Thienopyranones 6. Synthesis of seleno and telluro isocoumarins 7. Synthesis of a-pyranone fused with nitrogen containing heterocycles 8. Synthesis of phosphaisocoumarins 9. Synthesis of nature's isocoumarins 10. Synthesis of isocoumarins of pharmacological interest 11. Isocoumarins in organic synthesis: Synthetic applications 12. Conclusions