Main description:

Optical coherence tomography (OCT) angiography is an important new imaging modality that is already being used by ophthalmologists in retina centers worldwide. It uses motion as intrinsic contrast, thus obviating the need to inject any intravenous dye. It uses infrared light that is invisible to the patient, and only requires few seconds per scan. This makes it both easier to use and much better tolerated by patients than traditional dye-based fluorescein angiography (FA) and indocyanine green (ICG) angiography.

Inside Optical Coherence Tomography Angiography of the Eye Drs. David Huang, Bruno Lumbroso, Yali Jia, and Nadia Waheed include detailed information on clinical applications and fundamental principles needed to understand and use this new technology. This includes information on high-speed OCT systems, algorithms to extract flow contrast, the appearance of the normal eye, the findings in myriad diseases, and tips on how to deal with artifact and pitfalls.

The 3-dimensional nature of OCT angiography provides visualization that was not possible before with either FA or ICG and readers will come to appreciate how this enables the visualization of previously difficult to image vascular beds such as the 4 retinal vascular plexuses (radial peripapillary, superficial, intermediate, and deep), the choriocapillaris, and the deeper choroidal vessels.

Given its noninvasive nature and ease of use, OCT angiography imaging is rapidly taking an important place in everyday ophthalmology and may soon replace fluorescein angiography in everyday practice.

Optical Coherence Tomography Angiography of the Eye is designed to be the definitive text on this cutting-edge technology for the retina specialist and comprehensive ophthalmologist.

Contents:

Dedication

Acknowledgments

About the Editors

Contributing Authors

Introduction

Part I: Principles and Methods

Chapter 1 Optical Coherence Tomography Systems for Angiography

Gangjun Liu, PhD; Alex D. Pechauer, BS; David Huang, MD, PhD; and James G. Fujimoto, PhD

Chapter 2 Optical Coherence Tomography Angiography Algorithms

Yali Jia, PhD; Simon S. Gao, PhD; and David Huang, MD, PhD

Chapter 3 Cross-Sectional and En Face Visualization of Posterior Eye Circulations

Yali Jia, PhD; Bruno Lumbroso, MD; Simon S. Gao, PhD; David Huang, MD, PhD;
and David J. Wilson, MD

Chapter 4 Cross-Sectional and En Face Visualization of Normal Anterior Eye Circulations

Yan Li, PhD; Yali Jia, PhD; David Huang, MD, PhD; and Alison H. Skalet, MD, PhD

Chapter 5 Artifacts in Optical Coherence Tomography Angiography

Simon S. Gao, PhD; Yali Jia, PhD; and David Huang, MD, PhD

Chapter 6 Quantification

Yali Jia, PhD; Acner Camino, PhD; Miao Zhang, PhD; Simon S. Gao, PhD;
and David Huang, MD, PhD

Chapter 7 Optical Coherence Tomography Angiography: Terminology

David Huang, MD, PhD and Simon S. Gao, PhD

Chapter 8 Optical Coherence Tomography Angiography on the Optovue AngioVue With
Split-Spectrum Amplitude-Decorrelation Angiography and DualTrac Motion Correction

Tony Ko, PhD and Jay Wei, MS

Chapter 9 Optical Coherence Tomography Angiography: Optical Microangiography

Ruikang K. Wang, PhD; Qinqin Zhang, PhD; Giovanni Gregori, PhD;
and Philip J. Rosenfeld, MD, PhD

Chapter 10 Optical Coherence Tomography Angiography Imaging With Topcon's One-Micrometer
Wavelength Swept Source Optical Coherence Tomography

Charles Reisman, MS; Atsushi Kubota, MS; Masahiro Akiba, PhD;
Catharine Chisholm, PhD; and Michael J. Sinai, PhD

Chapter 11 Spectral Domain Optical Coherence Tomography
Angiography Using NIDEK RS-3000 Advance

Mayss Al-Sheikh, MD and SriniVas R. Sadda, MD

Part II: Retinal Diseases

Chapter 12 Exudative Neovascular Age-Related Macular Degeneration
Type 1, 2, and Mixed Choroidal Neovascularization

Bruno Lumbroso, MD; Steven T. Bailey, MD; Yali Jia, PhD; Marco Rispoli, MD;
and Maria Cristina Savastano, MD

Chapter 13 Short- and Long-Term Response of Choroidal
Neovascularization to Anti-Angiogenic Treatment

Bruno Lumbroso, MD; Steven T. Bailey, MD; Yali Jia, PhD; Marco Rispoli, MD;
and Maria Cristina Savastano, MD

Chapter 14 Nonexudative Neovascular Age-Related Macular Degeneration

Steven T. Bailey, MD; Ching J. Chen, MD; and Yali Jia, PhD

Chapter 15 Type 3 Neovascularization-Retinal Angiomatous Proliferation

Anna C.S. Tan, MBBS, FRCSED; Kunal K. Dansingani, MA, FRCOphth;
and K. Bailey Freund, MD

Chapter 16 Non-Neovascular Age-Related Macular Degeneration

Ricardo N. Louzada, MD; Nadia K. Waheed, MD, MPH; Jay S. Duker, MD;
and Mark Lane, MBBS Honors

Chapter 17 Polypoidal Choroidal Vasculopathy

Min Wang, MD, PhD; Simon S. Gao, PhD; and Yali Jia, PhD

Chapter 18 Optical Coherence Tomography Angiography of Macular Telangiectasia Type 2

Ching J. Chen, MD; Brian Tieu, MD, PhD; and Matthew Olson, CRA

Chapter 19 Central Serous Chorioretinopathy

Eduardo A. Novais, MD; Mark Lane, MBBS Honors;
Nadia K. Waheed, MD, MPH; and Jay S. Duker, MD

Chapter 20 Choroidal Neovascularization of Other Causes

Brian K. Do, MD; Richard I. Kaplan, MD; Patricia Garcia, MD;
Andre Romano, MD; and Richard Rosen, MD;

Chapter 21 Nonproliferative Diabetic Retinopathy

Thomas Hwang, MD; Yali Jia, PhD; Miao Zhang, PhD; and David J. Wilson, MD

Chapter 22 Proliferative Diabetic Retinopathy

Emily D. Cole, BS; Nadia K. Waheed, MD, MPH; and Jay S. Duker, MD

Chapter 23 Retinal Venous Occlusion

Marco Rispoli, MD and Bruno Lumbroso, MD

Chapter 24 Retinal Arterial Occlusion

Xiaogang Wang, MD, PhD; Jing Dong, MS; and Yading Jia, BS

Chapter 25 Inherited Retinal Degenerations

Rachel Patel, MD; Simon S. Gao, PhD; Paul Yang, MD, PhD; Richard G. Weleber, MD;
David J. Wilson, MD; and Mark Pennesi, MD, PhD

Chapter 26 Pathological Myopia

Leonardo Mastropasqua, MD and Luca Di Antonio, MD, PhD

Chapter 27 Flow Characteristics in Retinal Vasculitis Using
Optical Coherence Tomography Angiography

Phoebe Lin, MD, PhD; Miao Zhang, PhD; and Liang Liu, MD

Chapter 28 White Dot Syndromes

Philipp K. Roberts, MD; Lee Jampol, MD; and Amani A. Fawzi, MD

Chapter 29 Optical Coherence Tomography Angiography in
Choroiditis, Retinitis, and Vasculitis

Andre Romano, MD; Rubens Belfort Jr, MD, PhD; and Daniela Ferrara, MD, PhD

Chapter 30 Melanocytic Tumors

Alison H. Skalet, MD, PhD; David Huang, MD, PhD; Yali Jia, PhD; and Yan Li, PhD

Chapter 31 Radiation Maculopathy

Alexandre Matet, MD; Aude Ambresin, MD; Gilda Cennamo, MD; and Leonidas Zografos, MD

Part III: Optic Nerve Diseases

Chapter 32 Optical Coherence Tomography Angiography in Primary Open-Angle Glaucoma

David Huang, MD, PhD; Liang Liu, MD; and Michel Puech, MD, MSC

Chapter 33 Primary Angle-Closure Glaucoma

Chunhui Jiang, MD, PhD and Xinghuai Sun, MD, PhD

Chapter 34 Neurodegenerative Diseases

Albert J. Augustin, MD and Christian Dempe

Part IV: Anterior Diseases

Chapter 35 Angiography of the Cornea Using Optical Coherence Tomography

Winston Chamberlain, MD, PhD; Afshan Nanji, MD, MPH; David Huang, MD, PhD;
and Yan Li, PhD

Financial Disclosures

Index