Main description:

This book is a concise guide that provides an easy to follow template for other physicians to develop similar stem cell based treatments within their specialty. It identifies and summarizes the current world-wide orthopedic stem cell trials. Organized into three sections, Orthopedic Stem Cell Surgery presents clinical studies that examine the procedures for setting up and implementing stem cell surgery within the specialty of orthopedics. Chapters maintain an accessible narrative while also addressing complex studies related to orthopedic stem cell surgery. A sister text to the recently published, Retinal and Optic Nerve Stem Cell Surgery, and Neurologic Stem Cell Surgery this expertly written book examines critical Institutional Review Board (IRB) approved studies.

Contents:

Section 1. Rotator Cuff Repair

1. Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair - Rush University Medical Center, Chicago, Illinois

2. Bone Marrow Derived Stem Cells for the Treatment of Rotator Cuff Tears - Stanford University, Redwood City, California

3. Regenexx (TM) SD Versus Exercise Therapy for Rotator Cuff Tears - Centeno-Schultz Clinic, Broomfield, Colorado

4. Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection Into Partial Thickness Rotator Cuff Tears - Sanford Orthopedics and Sports Medicine, Fargo, North Dakota & Sioux Falls, South Dakota

5. Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears - Arizona Research Center, Phoenix, Arizona, United States; Biosolution research, La Mesa, California, United States; Lotus Clinical Research, LLC, Pasadena, California, United States; (and 8 more locations...)

6. Clinical Study on Mesenchymal Stem Cells Used in the Reconstruction Surgery of the

Supraspinatus Muscle Lesions - Petr Smid, Znojmo, Czech Republic, Czechia

7. Efficacy of Microfragmented Lipoaspirate Tissue in Arthroscopic Rotator Cuff Repair - U.O.C. 1a Divisione, Azienda Socio Sanitaria Territoriale Centro Specialistico Ortopedico, Traumatologico Gaetano Pini-CTO; Milano, Milan, Italy, IRCCS Policlinico San Donato , San Donato Milanese, Milan, Italy

8. Mesenchymal Stem Cells in Rotator Cuff Repair - Universidade de Sao Paulo, Sao Paulo, SP, Brazil

9. Treatment of Tendon Disease Using Autologous Adipose-derived Mesenchymal Stem Cells - Weiliang Shen, Hangzhou, Zhejiang, China

10. Adipose-derived Mesenchymal Stem Cells in Osteoarthritis - Life Clinic, Warsaw, Mazovian, Poland

Section 2. Knee Osteoarthritis

1. Impact of Mesenchymal Stem Cells in Knee Osteoarthritis - University Hospital Cleveland Medical Center, Cleveland, Ohio, United States

2. Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES) - Andrews Institute, Gulf Breeze, Florida; The Emory Clinic, Atlanta, Georgia; Duke University, Durham, North Carolina; Sanford Health, Fargo, North Dakota; Sanford Health, Sioux Falls, South Dakota

3. Early Regenerative Intervention for Post-Traumatic Osteoarthritis (ERIPTO) - The Center for Primary Care and Sports Medicine, Aurora, Illinois, United States; Affinity Health Research Institute, Oak Brook, Illinois, United States; Genesis Orthopedics and Sports Medicine, Oak Brook, Illinois

4. Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction - The Steadman Clinic, Vail, Colorado

5. Open Ended Trocar vs. Fenestrated Blunt Trocar in Bone Marrow Aspirate for Osteoarthritis - Advanced Orthoaedic Specialists, Fayetteville, Arkansas

6. The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis - Stanford University, Stanford, California, United States

7. A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells - Sanford Orthopedics and Sports Medicine, Sioux Falls, South Dakota

8. Stem Cell and Growth Factor Injury and Arthritis Clinical Research Study - Stone Research Foundation, San Francisco, California, United States

9. Adipose-derived Mesenchymal Stem Cells in Osteoarthritis - Life Clinic, Warsaw, Mazovian, Poland

10. Wharton's Jelly-derived Mesenchymal Stem Cells in Osteoarthritis - Life Clinic, Warsaw, Mazovian, Poland

11. A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis (ADIPOA-2) - UH Montpellier, Montpellier, France

12. Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair (AURA) - Chapel Allerton Orthopaedic Centre, Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom

13. Subchondral and Intra-articular Application of Bone Marrow Concentrate for Knee Unicompartmental OA (Marrow Mule) - Istituto Clinico Humanitas, Rozzano, Milano, Italy

14. Treatment of Early Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells - Qilu hospital of Shandong University, Jinan, Shandong, China

15. Clinical Study of Pulp Mesenchymal Stem Cells in the Treatment of Primary Mild to Moderate Knee Osteoarthritis - Changhai hospital, Shanghai, China

16. Very Small Embryonic-like Stem Cells for Knee Osteoarthritis - Biological treatment center in Fuda cancer hospital, Guangzhou, Guangdong, China

17. Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis - China-Japan Friendship Hospital, Beijing, China; The Second Affiliated hospital of Zhejiang University School of Medicine, Hangzhou, China; Huashan Hospital Affiliated to Fudan University, Shanghai, China, (and 3 more locations...)

18. Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells (GXCPC1) for Knee Osteoarthritis - GWOXI Stem CellApplied Technology Co., Ltd., Hsinchu, Taiwan

19. Treatment of Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells - Yantai Yuhuangding Hospital, Yantai, Shandong, China

20. Clinical Study of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) for Treatment of Knee Osteoarthritis - Liaocheng city people's hospital, Liaocheng, Shandong, China

21. Mesenchymal Stem Cell Transplantation for Osteoarthritis - Yantai Yuhuangding Hospital, Yantai, Shandong, China

22. Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury - Qilu hospital of Shandong University, Jinan, Shandong, China

23. Adipose-derived Stem Cells (ADSCs) for Knee Osteoarthritis - Taipei Veterans General Hospital, Taipei, Taiwan; Chang Gung Memorial Hospital Linkou, Taoyuan City, Taiwan

24. Allogeneic Bone Marrow MSC Therapy for Knee Osteoarthritis - Taipei Veterans General Hospital, Taipei, Taiwan

25. Evaluate Safety and Explore Efficacy of SMUP-IA-01 in Patients With Knee Osteoarthritis - Seoul National University Hospital, Seoul, Jongno-gu, Korea, Republic of

26. Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects, Adipose-derived mesenchymal progenitor cells - Shanghai ninth people's

hospital, Shanghai, Shanghai, China

27. Follow-up Study for Participants Jointstem Clinical Trial - KyungHee University Gangdong Hospital, Seoul, Korea, Republic of; GangNam Severance Hospital, Seoul, Korea, Republic of

28. A Phase 3 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis - Chungbuk National University Hospital, Cheongju-si, Korea, Republic of; Yeungnam University Hospital, Daegu, Korea, Republic of; Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of; (and 9 more locations...)

29. Follow-up Safety and Efficacy Evaluation on Subjects Who Completed Phase I Clinical Trial - Seoul national University Hospital, Seoul, Jongno-gu, Korea, Republic of Korea

30. Clinical Study of Intra Articular Injection of Catholic MASTER Cell (Bone Marrow Derived

Mesenchymal Stem Cell) in Knee Osteoarthritis (MSC-OA) - Catholic University of Korea, Seoul, Korea, Republic of

31. Follow-up Study for Participants of Jointstem Phase 3 Clinical Trial - Chungbuk National University Hospital, Cheongju-si, Korea, Republic of; Yeungnam University Hospital, Daegu, Korea, Republic of; Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of;

(and 10 more...)

32. Investigator Initiated Trial to Evaluate the Efficacy and Safety of Intra-articular Injection

of ADMSC Compared to Negative Control After High Tibial Osteotomy in the Osteoarthritis Patients. - KyungHee University, Gangdong Hospital, Seoul, Korea, Republic of

33. Autologous Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis - Second affiliated hospital, school of medicine, Zhejiang Uni., Hangzhou, Zhejiang, China

34. The Safety/Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife (R)-O) Therapy for Patients With Osteoarthritis - Xiangya Hospital Central South University, Changsha, Hunan, China

35. WHARTON JELLY ORIGINATED MESENCHIAL STEM CELL in GONARTHROSIS (WHAMKO) - Erciyes University Faculty of Medicine, Melikgazi, Kayseri, Turkey

36. Use of Adipose Tissue Derived Mesenchymal Stem Cells for Knee Osteoarthrosis - Cell Therapy Center, Amman, Jordan

37. Use of Wharton Jelly Derived Mesenchymal Stem Cells for Knee Osteoarthrosis - Cell Therapy Center, Amman, Jordan

38. Effects of MAT Versus Steroid Injection in Knee Osteoarthritis (ST MAT-knee Study)-

American University of Beirut Medical Center, Beirut, Lebanon

39. Implantation of Allogenic Mesenchymal Stem Cell From Umbilical Cord Blood for Osteoarthritis Management - Universitas Indonesia, Jakarta Pusat, Jakarta, Indonesia

40. Comparative Effectiveness of Arthroscopy and Non-Arthroscopy Using Mesenchymal Stem Cell Therapy (MSCs) and Conditioned Medium for Osteoartrithis (OA) - Gatot Soebroto Hospital

Jakarta Pusat, DKI Jakarta, Indonesia

41. The Evaluation of Safety and Effectiveness of Intraarticular Administration of

Autologous Stromal-Vascular Fraction of Adipose Tissue Cells for Treatment of Knee

Joint Arthrosis - Swiss Medica XXI Century S.A., Moscow, Russian Federation; IM Clinic, Belgrade, Serbia

42. Efficacy of Bone-marrow-derived and Placenta-derived Multipotent Mesenchymal Stem / Stromal Cells for Osteoarthritis - Institute of Cell Therapy, Kyiv, Ukraine

43. Bone Marrow Versus Adipose Autologous Mesenchymal Stem Cells for the Treatment of

Knee Osteoarthritis - Omnihospital, Guayaquil, Guayas, Ecuador

Section 3. Labral Repair

1. BMAC Use With Labral Repair - MGH, Massachusetts General Hospital, Boston, Massachusetts, United States