Main description:

Pediatric musculoskeletal infections are common globally and represent about 1-2% of all pediatric hospital admissions in the developed world and about 10-20% of admissions in the developing countries. If untreated or treated inadequately, pediatric bone and joint infections can cause significant mortality and morbidity. The functional and economic burden to the family and community at large also presents a significant public health problem.

This book serves as an evidence-based, comprehensive review of the current concepts for the early diagnosis and management of pediatric musculoskeletal infections. Currently, there are no comprehensive, easily accessible books on this topic. This first of its kind book also uses a multidisciplinary and global approach by including contributions from editors and authors worldwide. The long-term goal of this text is to help improve the quality of care provided to children with musculoskeletal infections improve patient safety, reduce the cost of care, and add value to the care provided to these children and thus reduce the economic burden.

Broken up into five sections, the first part of this text covers the epidemiology, microbiology, pathological consequences, antibiotic therapies, systemic effects, and imaging modalities of pediatric musculoskeletal infections. Section two takes a detailed look at acute pediatric musculoskeletal infections. Infections discussed in this section include acute hematogenous osteomyelitis, septic arthritis, pyomyositis, complex musculoskeletal infections, musculoskeletal infections in the neonate and acute surgical site infection after pediatric orthopedic surgery. Section three focuses on chronic osteomyelitis and its sequelae. Section four examines anatomic region-specific considerations in musculoskeletal infections. The topics that are expanded upon are epiphyseal osteomyelitis, Pediatric hand and foot infections, tuberculosis of the axial and the appendicular skeleton, and non-tuberculous infections of the spine. Finally, the fifth section includes an overview of less common musculoskeletal conditions such as, fungal infections, brucellosis, hydatid disease, gas gangrene, viral musculoskeletal infection and meningococcal infections.

Written by experts in the field, Pediatric Musculoskeletal Infections: Principles and Practice serves as an easily accessible resource for a global audience of healthcare providers from multiple disciplines to aid them in making informed decisions while managing pediatric bone and joint infections. Paediatricians, orthopedic surgeons, infectious disease physicians, radiologists, pathologists, family physicians and any other healthcare providers involved in the care of children with musculoskeletal infections will find immense value in this reference as will medical students, residents and fellows.

Contents:

Section 1: General principles

Epidemiology of musculoskeletal infections

The Microbiology of MSK infections and antibiotic therapies

Pathology of musculoskeletal infections

Imaging modalities to diagnose musculoskeletal infections

Infection mimics: differential diagnoses of musculoskeletal infections

MRSA and virulent MSSA infections

Systemic effects of musculoskeletal infections and ICU management

Local antibiotic drug delivery systems for musculoskeletal infections

Evidence based management of musculoskeletal infections

Section 2: Acute musculoskeletal infections

Acute hematogenous osteomyelitis

Septic arthritis

Pyomyositis

Musculoskeletal infections in the neonate

Subacute osteomyelitis

Surgical site infection in pediatric orthopaedic surgery

Surgical site infection in spine surgery

Infections related to external fixators

Pediatric musculoskeletal infections: a LMIC perspective

Section 3: Chronic musculoskeletal infections and their sequelae

Chronic hematogenous Osteomyelitis

Post-traumatic chronic osteomyelitis

Chronic non-bacterial recurrent osteomyelitis (Chronic non-infective osteitis)

Pathological fractures with osteomyelitis

Post infective deformities: strategies for limb reconstruction

Sequelae of septic arthritis of the hip and late reconstruction

Post infective bone gap management of the upper extremity

Post infective bone gap management of the lower extremity

Post infective bone gap management: Induced membrane technique

Section 4: Region specific musculoskeletal infections

Epiphyseal osteomyelitis

Pediatric hand infections

Pediatric foot infections

Tuberculosis of the axial skeleton

Tuberculosis of the appendicular skeleton

Non-tuberculous infections of the spine

Section 5: Uncommon musculoskeletal infections

Musculoskeletal infections in immunocompromised children

Fungal infections

Necrotizing fasciitis

Gas gangrene

Meningococcal infections

Brucellosis, Hydatid disease, and viral osteomyelitis