Main description:

Alzheimer's disease is the most prevalent form of dementia. Although it was discovered about a century ago, the first drugs applied in treatment were only introduced in therapy in the last 30 years.
This book focuses on the clinical pharmacology of drugs that aim to delay the progression of Alzheimer's disease, such as anticholinesterases and glutamate receptor antagonists, as well as treatment for the behavioral changes caused by the progression of the disease: antidepressants, antipsychotics, anxiolytics, and mood stabilizers.
In addition, it describes important information about the pathophysiology and diagnostic methods of Alzheimer's disease, emergency situations conditioned by the dementia process, and presents new perspectives for the treatment of Alzheimer's disease. The ten chapters cover topics such as mechanism of action, dosage regimen, adverse reactions, drug interactions, toxicity profiles, among other information of clinical relevance. The work comprises evidence-based studies, providing a valuable resource for analyzing, prescribing and monitoring patients being treated for Alzheimer's disease.
Written by experts with solid professional experience, this book will appeal to pharmacologists, geriatricians, neurologists, psychiatrists, biomedical clinicians, and other healthcare professionals.

Contents:

1. IntroductionGustavo Alves Andrade dos Santos 2. Principles of Pharmacology in DementiaFrancisco Assis Carvalho Vale, Judith Thomas Tayra, Carina Tellaroli Spedo3. The Viability of Treatment Conditioned to the Pathophysiology of Alzheimer's DiseaseFabricio Ferreira de Oliveira4. The Use of Esterase InhibitorsGustavo Alves Andrade dos Santos, Carolina Witchmichen Penteado Schmidt, Karina Pedrotti Forlenza5. Pharmacology of NMDA (N-methyl-D-aspartate) receptor antagonists in Alzheimer's DiseaseCarolina Witchmichen Penteado Schmidt 6. Supportive Pharmacological TreatmentKaleu Mormino Otoni, Karla Bruna Nogueira Torres Mormino, Sandna Larissa Freitas dos Santos, Maria Liliane Luciano Pereira7. Herbal Medicines and SupplementsEduardo Carita 8. Emergency SituationsMilena Carvalho Libardi, GuilhermeRiccioppo Rodrigues, Rui Kleber Martins Filho9. Relationships between Treatment and Clinical EvaluationsPaulo Pardi, Gustavo Alves Andrade dos Santos10. New Perspectives for Treatment in Alzheimer's DiseaseJulia Cunha Loureiro, Marcos Vasconcelos Pais, Luiz Fernando de Almeida Lima e Silva, Orestes Vicente Forlenza