Main description:

This invaluable collection of high-quality articles on pharmacology is taken from the tried-and-tested Meyers' Encyclopedia of Molecular Cell Biology and Molecular Medicine whose editorial board includes 12 Nobel laureates. Divided into four main sections, this attractive handbook covers essential fields in pharmacology, from drug development to cancer and gene therapy. The articles are uniformly structured for ease of use and carefully designed to serve readers of all levels of expertise. Each chapter includes a glossary of the most important keywords, a concise summary of the article and a comprehensive literature references. The book is a must have reference work for pharmacology departments in academia as well as for the pharmaceutical industry.

Contents:

I DRUG DEVELOPMENT Medicinal Chemistry Biotransformations of Drugs and Chemicals Disposition and Clearance Prediction of Drug Bioavailability Pharmacokinetics and Pharmacodynamics of Biotech Drugs Targeting and Intracellular Delivery of Drugs Pharmacogenomics and Drug Design Chemistry, Biology, and Drug Design of Synthetic Peptides: Structure-based Drug Design and NMR-based Screening Receptor Targets in Drug Discovery Therapeutic Compounds in Nature as Leads for New Pharmaceuticals Cancer Stem Cells Plant-based Expression of Biopharmaceuticals II INNOVATIVE THERAPEUTIC APPROACHES Genetic Engineering of Antibody Molecules Exploiting Model Organisms for Disease Intervention Pharmacology and Emerging Clinical Application of RNA Biochemistry of HIV Therapeutics Xenotransplantation in Pharmaceutical Biotechnology RNA Interference Genomic Approaches in Targeted Therapy Therapeutic Angiogenesis Oligonucleotides III CANCER THERAPEUTICS Molecular Oncology Theoretical Foundations of Cancer Chemotherapy Antitumor Steroids Immunotoxins and Recombinant Immunotoxins in Cancer Therapy IV GENE THERAPY Liposome Gene Transfection Genetic Vaccination Vectors and Gene Therapy Somatic Gene Therapy Virus-free Gene Transfer Systems in Somatic Gene Therapy Gene Therapy and Cardiovascular Diseases Vector System: Plasmid DNA Vector Targeting in Gene Therapy