Main description:

Progress in Medicinal Chemistry, Volume 59, provides a review of eclectic developments in medicinal G139 chemistry. Each chapter is written by an international board of authors, with this release focusing on Small Molecules - Giant Leaps for Immuno-Oncology, Reviewing P2X7, Reviewing ASK1, and Reviewing DNA-encoded libraries.

Contents:

Small molecules-Giant leaps for immuno-oncology
Lisa Koetzner, Bayard Huck, Sakshi Garg and Klaus Urbahns

P2X7 receptor antagonists for the treatment of systemic inflammatory disorders
Christine F. Gelin, Anindya Bhattacharya and Michael A. Letavic

Discovery and development of ASK1 inhibitors
Reginald Brys, Karl Gibson, Tanja Poljak, Steven Van Der Plas and David Amantini

An overview of DNA-encoded libraries-A versatile tool for drug discovery

Daniel Madsen, Carlos Azevedo, Iolanda Micco, Lars Kolster Petersen and Nils Jakob Vest Hansen