Main description:

Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability and folding, and explains how interactions in macromolecular structures determine protein function. Intended for a one-semester course in biochemistry or biophysical chemistry with a focus on proteins, this textbook emphasizes the logic underlying biophysical chemical principles. Problems throughout the book encourage statistical and quantitative thinking. The text is ideal for senior undergraduates, first year graduate students, and practitioners in chemistry, biochemistry, biology, and biophysics.

Contents:

1.Statistical Thermodynamics of Biological Molecules 2.Protein Structure 3.Evolution of Protein Sequence and Structure 4.Protein Stability 5.Protein Folding 6.Binding, Allostery, and Cooperativity 7.Enzyme Kinetics Appendix A. Calculation of the excess heat capacity curve of protein thermal denaturation Appendix B. Calculation of the average helicity from the partition function Appendix C. Solution of rate equations for two-state system