Published December, 2013
By Munther A. Khamashta, Manuel Ramos-Casals and Xavier Bosch
Publisher: Springer (Springer Basel)
Series: Milestones in Drug Therapy
Rating:
Availability: Available

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjoegren syndrome, ANCA-associated vasculitis and cryoglobulinemia.

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Published November, 2013
By Isabelle Couillin, Virginie Petrilli and Fabio Martinon
Publisher: Springer (Springer Basel)
Series: Progress in Inflammation Research
Rating: 1.00
Availability: Available

The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18.

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Published November, 2013
By Alexandre Trifilieff
Publisher: Springer (Springer Basel)
Series: Milestones in Drug Therapy
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Availability: Available

Here is a comprehensive overview of the development of Onbrez Breezhaler, a newly approved once-daily inhaled beta2 agonist for treating COPD. Covers design and pre-clinical pharmacology of the molecule, early clinical development, efficacy studies and more.

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Published November, 2013
By Nathalie Vergnolle and Michel Chignard
Publisher: Springer (Springer Basel)
Series: Progress in Inflammation Research
Rating: 1.00
Availability: Available

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Published November, 2013
By Stefan F. Martin
Publisher: Springer (Springer Basel)
Series: Experientia Supplementum
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Availability: Available

The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response.

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Published September, 2013
By Anton G. Kutikhin and Arseniy E. Yuzhalin
Publisher: Springer (Springer Basel)
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Availability: Available

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail.

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Published September, 2013
By Saskia Dombrowski
Publisher: Springer (Springer Basel)
Series: BVL-Reporte
Rating:
Availability: Not available (reason unspecified)

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Published August, 2013
By Saskia Dombrowski
Publisher: Springer (Springer Basel)
Series: BVL-Reporte
Rating:
Availability: Available

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Published August, 2013
By V. Craig Jordan, Philipp Y. Maximov and Russell E. McDaniel
Publisher: Springer (Springer Basel)
Series: Milestones in Drug Therapy
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Availability: Available

Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a "failed morning after contraceptive" to become the "gold standard" for the treatment of breast cancer.

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Published July, 2013
By Immacolata Castellano and Antonello Merlino
Publisher: Springer (Springer Basel)
Series: SpringerBriefs in Biochemistry and Molecular Biology
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Availability: Available

Gamma-Glutamyl Transpeptidases ( -GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the -glutamyl amide bond of glutathione to liberate cysteinylglycine.

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