Main description:

Semisynthesis of Bioactive Compounds and their Biological Activities explores the potential benefits of semisynthetic derivatives obtained from nature. Sections cover the natural distribution of parent compounds, semisynthesis and biological properties of semisynthetic derivatives, the applications of semisynthetic derivatives in diverse fields such as drug delivery, food production and medicine, an explanation of the current resistance mechanisms of antibiotics, clinical applications of semisynthetic analogues, the functions of plant alkaloids on human health, potential agricultural biotechnology in semisynthetic derivatives, and semisynthesis of natural products under greener conditions, this book provides a comprehensive resource on the topics presented.

Sections include information about alternative sources of energy and superior greener technologies (microwave, sonochemistry), alternative reaction media (water, supercritical CO2, ionic liquids) and alternative eco-friendly catalysts (biocatalysts). This book will be an excellent resource for academicians, researchers and students focusing on synthesis as well as the biological community and industry professionals in drug development.

Contents:

1. Introduction
2. Semisynthesis of Antibiotics
3. Semisynthesis of Alkaloids
4. Semisynthesis of Flavones
5. Semisynthesis of Lignans
6. Semisynthesis of Phenolic Compounds
7. Semisynthesis of Anthocyanins
8. Semisynthesis of Natural Products at Room Temperature (R2)
9. Semisynthesis of Natural Products under Greener Conditions
10. Semisynthesis of Natural Products through Insertion of Oxygen Atom under Metal-free Conditions
11. An adaptation of organic reactions in the bioactive compounds industry (R1)
12. Regulatory aspects of the novel derivative as nutraceuticals (R1)
13. Computational chemistry of Natural Product Analogues (R2)
14. Semi-synthesis for neglected and tropical diseases (R2)