Main description:

Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.

The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.

Contents:

Preface Akon Higuchi, Yinghong Zhou and Shih-Hwa Chiou 1. Introduction to stem cells Zeyu Tian 2. Stem cell engineering Pingping Han 3. Xeno-free culture and proliferation of hPSCs on 2D biomaterials Akon Higuchi and Suresh Subbiah 4. 3D scaffold preparation for stem cell culture and differentiation Yasuhiko Tabata 5. GMP grade production of hPSCs I-Ping-Molly Yang 6. Human hepatic stem cell assay Saeko Akiyama 7. Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment Katsuhisa Matsuura 8. Stem cell therapy for osteoarthritis Xiaoxin Wu 9. hPSC-derived RPE transplantation for the treatment of macular degeneration Qian Liu 10. Universal and hypoimmunogenic pluripotent stem cells for clinical usage Tzu-Cheng Sung 11. Clinical usage of dental stem cells Yinghong Zhou 12. Stem and progenitor cell therapies in cutaneous wound healing Abbas Shafiee 13. Application of iPSC and ESC derived Muller glia in retinal degenerative disease Guoge Han 14. Stem cells as a therapy for diabetes Bernard Edward Tuch 15. Stem cells challenges and opportunities Akihiro Umezawa