Main description:

This volume provides a history of and an update on the functional status of the NMDA receptors. The NMDA receptors are essential for neuronal development, synaptic plasticity, learning, and cell survival. It covers molecular, cellular, anatomical, biochemical, and behavioral aspects, to highlight their distinctive regulatory properties, their functional significance, and their therapeutic potential in a number of diseases. A group of international experts discuss the development of NMDA receptors, their basic functions, and how they are implicated in a wide range of diseases including depression, psychosis, and pain.

Contents:

Chapter 1. Overview of the NMDA receptor
by Hisashi Mori
2. Synaptic and extra-synaptic NMDA receptors in the CNSby Thomas Papouin and Stephane H.R. Oliet
3. Functional Distribution and Regulation of the NMDAR in the Kidney, Heart and Parathyroid Glandby Milica Bozic and Jose M. Valdivielso
4. Rapid Antidepressant Activity of Ketamine beyond NMDA Receptorby Kenji Hashimoto
5. D-aspartate, an atypical amino acid with NMDA receptor agonist features: involvement in schizophreniaby F. Errico and A. Usiello1
6. NMDA Receptors and Signaling in Chronic Neuropathic Painby Geoffroy Laumet, Shao-Rui Chen, and Hui-Lin Pan
7. Role of NMDA receptors in pancreatic isletsby Okka Scholz, Alena Welters and Eckhard Lammert
8. NMDA Receptor in Boneby Yukio Yoneda