Main description:

This monumental, one-stop encyclopedia covers all levels, integrating molecular, cellular and systemic processes into a single knowledge base that encompasses many disciplines and approaches. Clearly divided into three parts over nine volumes, the modular structure allows for easy access with topical volumes and volume sets facilitating browsing and in-depth study. Essential for everyone working in cell biology and molecular medicine.

Contents:

Part I: MOLECULAR MACHINERY (Vols. 1-3) Extracellular and Plasma Membrane Events - ligands and receptor recognition - receptors - ion channels - membrane topology Intracellular Transmission Events - protein networks - protein phosphorylation / dephosphorylation - ubiquitination / deubiquitination - G protein signaling - lipid signaling - cyclic nucleotides - calcium signaling Nuclear Events - nuclear receptors - transcription factors - checkpoints - nuclear topology PART II: CELLULAR PROCESSES (Vols. 4-6) Cell Growth and Gene Expression - cell proliferation - chromatin as a signaling platform - DNA damage responses - translational and post-translational control Cellular Responses - apoptosis - stress responses - protein folding - senescence Dynamic Cellular Processes - adhesion and cell polarity - membrane traffic - cell migration - cytoskeleton The Cellular Masterplan - signaling topology - systems biology of signaling PART III: SYSTEMIC PROCESSES AND DISEASES (Vols. 7-9) Immunology Inflammation Angiogenesis Cancer Stem Cells Ageing Metabolism Development Neurotransmission