Main description:

This book provides comprehensive information on transcatheter aortic valve implantation (TAVI), which was introduced for the treatment of aortic valve disease less than two decades ago. It explains how TAVI has delivered satisfactory results even in high and intermediate risk patients and outlines how it continues to evolve, thus requiring awareness of state of the art approaches to indication, risk stratification, device choice, procedure, and follow-up. In addition, it reports on the complex and multidisciplinary approach needed to maximize the efficacy, safety, and appropriateness of TAVI, providing detailed clinical, interventional and surgical perspectives focusing on the development of this cardiovascular intervention.

Starting with the history of TAVI, addressing the interventional anatomy of aortic valve disease, and reporting on the expert authors' day-to-day experiences, this highly informative book offers an essential update for all cardiologists and surgeons interested in transcatheter aortic valve implantation, as well as any clinician, decision-maker and stakeholder involved in patient selection, procedural management, and follow-up.

Contents:

I - Pathophysiological and translational perspectives.- 1 History of transcatheter aortic valve implantation.- 2 Interventional anatomy of aortic valve disease.- 3 Pathophysiology of aortic.- 4 Pathophysiology of aortic regurigation.- 5 Pathophysiology of degenerated bioprosthesis.- 6 Role of inflammation in native and prosthetic aortic valve disease.- 7 Predictive computational models of transcatheter aortic valve implantation.- 8 Hemodynamic issues with transcatheter aortic valve implantation.- 9 Risk scores for aortic valve.- II Clinical perspectives.- 10 Role of rest and stress echocardiography in transcatheter aortic valve implantation.- 11 Role of computed tomography in transcatheter aortic valve implantation.- 12 Role of magnetic resonance imaging in transcatheter aortic valve implantation.- 13 Concomitant coronary artery disease and aortic stenosis.- 14 Comparison of transcatheter aortic valve implantation to medical therapy in prohibitive risk patients.- 15 Clinical and imaging follow-up after transcatheter aortic valve implantation.- 16 Biomarkers before, during and after transcatheter aortic valve implantation.- 17 Prognostic impact of aortic regurgitation and paravalvular leak.- 18 Leaflet motion abnormalities.- 19 Gender-related differences in transcatheter aortic valve implantation.- 20 Implementation issues for transcatheter aortic valve implantation: cost-effectiveness, wait-times and volume-outcome balance.- III Interventional perspectives.- 21 Transfemoral access management for transcatheter aortic valve implantation.- 22 Challenging anathomy for transcatheter aortic valve implantation.- 23 Abbott Vascular program for transcatheter aortic valve implantation.- 24 Boston Scientific program for transcatheter aortic valve implantation.- 25 Edwards program for transcatheter aortic valve implantation.- 26 JenaValve program for transcatheter aortic valve implantation.- 27 Medtronic program for transcatheter aortic valve implantation.- 28 Self-expanding vs balloon-expandable devices for transcatheter aortic valve implantation.- 29 Individualized device choice for transcatheter aortic valve implantation.- 30 Predilation for transcatheter aortic valve implantation.- 31 Postdilation for transcatheter aortic valve implantation.- 32 Embolic protection devices for transcatheter aortic valve implantation.- 33 Antithrombotic therapy during and after transcatheter aortic valve implantation.- 34 Contrast induced nephropathy and transcatheter aortic valve implantation.- 35 Conduction disorders and permanent pacemaker requirement after transcatheter aortic valve implantation.- 36 Systolic dysfunction and hemodynamic support in patients candidate for transcatheter aortic valve implantation.- 37 Radiation exposure in transcatheter aortic valve implantation.- 38 Procedure efficiency in transcatheter aortic valve implantation.- 39 Predictors of success for transcatheter aortic valve implantation.- 40 Learning curve, procedural volumes and relationship with clinical outcomes for transcatheter aortic valve implantation.- 41 Aortic valvuloplasty as bridge vs destination therapy.- IV Surgical perspectives.- 42 Role of the heart team in decision making for transcatheter aortic valve implantation.- 43 Alternative accesses for transcatheter aortic valve implantation.- 44 Comparison of transcatheter aortic valve implantation to surgery in intermediate risk patients.- 45 New approaches for aortic valve disease: from transcatheter aortic valve implantation to sutureless aortic valves.- 46 Hybrid procedures for aortic valve disease: transapical aortic valve implantation through lower left anterior mini-thoracotomy vs Edwards Intuity valve implantation through upper right anterior mini-thoracotomy.- V Future perspectives.- 47 Medical treatment for aortic valve disease.- 48 Transcatheter aortic valve implantation for pure aortic regurgitation.- 49 New-generation devices for transcatheter aortic valve implantation.- 50 Bioresorbable valve for transcatheter aortic valve implantation: tomorrow's world from preclinical to clinical.- 51 Focus on transcatheter aortic valve implantation in low risk patients.- 52 Conclusion.