Main description:

This volume explores the latest experimental techniques in animal models of PTSD and humans affected by PTSD. The methods discussed in this book cover topics such as translational research; addressing sex differences; highlighting the state-of-the-art of biomarker discovery in the development and maintenance of PTSD; and looks at new promising agents to enhance fear extinction retention that may help millions of individuals that suffer from this debilitating disorder worldwide. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Authoritative and thorough, Translational Methods for PTSD Research is a valuable resource that will help researchers understand and learn more about this important disorder.

Contents:

Series Preface...Preface...Table of Contents...Contributing Authors...
1. Translational Model of Infant PTSD Induction: Methods for Infant Fear ConditioningRoseanna M. Zanca, Sara Stanciu, Islam Ahmed, Christopher K. Cain, and Regina M. Sullivan
2. Periadolescent Social Isolation Effects on Extinction of Conditioned FearKatherine Drummond and Jee Hyun Kim
3. Using Virtual Reality to Study Fear and Extinction in Children and AdolescentsHilary A. Marusak, Craig Peters, Christine A. Rabinak 4. Assessing the Role of Sleep in the Regulation of Emotion in PTSDIhori Kobayashi, Mariana E. Pereira, Kilana D. Jenkins, Fred L. Johnson III, and Edward F. Pace-Schott 5. Pavlovian Conditioning and Extinction Methods for Studying the Neurobiology of Fear Learning in PTSDDylan B. Miller, Madeleine M. Rassaby, Zhenfu Wen, and Mohammed R. Milad
6. Reconciling Translational Disparities between Empirical Approaches to Better Understand PTSDSeth D. Norrholm, Timothy J. Cilley, Jr., and Tanja Jovanovic
7. An Integrative Model for Endophenotypes Relevant to Posttraumatic Stress Disorder (PTSD): Detailed Methodology for Inescapable Tail Shock Stress (IS) and Juvenile Social Exploration (JSE)Nathan D. Andersen, John D. Sterrett, Gabriel W. Costanza-Chavez, Cristian A. Zambrano, Michael V. Baratta, Matthew G. Frank, Steven F. Maier, and Christopher A. Lowry
8. Apolipoprotein E Isoform-Related Translational Measures in PTSD ResearchEileen Ruth Samson Torres, Andrea E. DeBarber, and Jacob Raber
9. Stress Immobilization Inducing Fear Extinction Deficits in Male and Female MiceEric Raul Velasco, Antonio Florido, Ignacio Marin, Patricia Molina, Laura Perez-Caballero, and Raul Andero
10. 5-HT Neural System Abnormalities in PTSD Model RatsHiroki Shikanai, Hirokazu Matsuzaki, Rina Kasai, Shota Kusaka, Tsugumi Shindo, and Takeshi Izumi 11. Animal Models of PTSD: The Role of Fear Conditioning Mariella B.L. Careaga, Carlos Eduardo Neves Girardi, and Deborah Suchecki
12. Combining Virtual Reality Exposure Therapy with Non-Invasive Brain Stimulation for the Treatment of Post-Traumatic Stress Disorder and Related Syndromes. A PerspectiveC. M. Vicario, M. A. Salehinejad, C. Lucifora, G. Martino, A. M. Falzone, G. Grasso, and M. A. Nitsche
13. Associating Aversive Task Exposure with Pharmacological Intervention to Model Traumatic Memories in Laboratory RodentsLucas Gazarini, Cristina A. J. Stern, and Leandro J. Bertoglio
14. Loudness Dependence of Auditory Evoked Potentials (LDAEP): A Promising Pre-Treatment Predictor of Selective Serotonin Reuptake Inhibitor (SSRI) ResponseSuzanne L. Pineles, Shivani Pandey, Rachel Shor, Ronnie F. Abi-Raad, Matthew O. Kimble, and Scott P. Orr 15. Preclinical Methods of Neurosteroid-Induced Facilitation of Fear Extinction and Fear Extinction Retention Luca Spiro Santovito and Graziano Pinna
Subject Index List...