Main description:

This book provides comprehensive, cutting-edge scientific data on acute and chronic tubulointerstitial nephritis, an area that has not been fully addressed in many nephrology textbooks. This book covers all relevant aspects of the disease, from historical aspects and pathogenesis to diagnosis, pathological findings, treatment, and prognosis and outcomes. The chapters also discuss both immune and non-immune mediated forms of the disease, as well as entities causing tubulointerstitial disease such as medications and toxins, infectious agents, autoimmune diseases, transplant rejection, genetic diseases, infiltrative disease and chronic kidney disease of unknown etiology. The text features up-to-date educational materials that will benefit both basic and clinical scientists. Written by experts in the field, Tubulointerstitial Nephritis is a valuable resource for clinicians, practitioners, researchers and trainees working in the field of nephrology and internal medicine.

Contents:

I. History and Epidemiology

1. A history of its conceptual evolution

2. Epidemiology of tubulointerstitial nephritis

II. Pathogenesis

3. Pathogenesis of Acute Tubulointerstitial Nephritis

III. Causes of Acute Tubulointerstitial Nephritis

4. Drugs associated with Acute Tubulointerstitial Nephritis

5. Viral-induced Tubulointerstitial Nephritis

6. Bacterial and parasitic-related tubulointerstitial nephritis

7. Tubulointerstitial nephritis due to autoimmune diseases

8. IgG4-Related Tubulointerstitial Disease

9. Anti-brush border antibody (ABBA)-associated tubulointerstitial disease

10. Transplant Rejection and Infection Associated Tubulointerstitial Nephritis

IV. Non-immune Mediated

11. Genetic Diseases Associated with Tubulointerstitial Nephritis

12. Cystinosis

13. Chronic tubulointerstitial nephritis: Hypokalemia, hyperoxaluria, and hyperuricemia

14. Non-immunological Causes of Tubulointerstitial Disease

15. Reflux and Obstructive Nephropathy

16. Aristolochic Acid Nephropathy and Balkan Nephropathy

17. Chronic Kidney Disease of Unknown Etiology

18. Infiltrative Disease of the Tubulointerstitium

V. Diagnosis

19. Clinical features and laboratory findings in acute tubulointerstitial nephritis

20. Imaging modalities for acute tubulointerstitial nephritis

21. Pathology of Tubulointerstitial Nephritis

VI. Treatment

22. Management of Tubulointerstitial Nephritis

VII. Prognosis/Outcomes

23. Prognosis and outcomes of acute tubulointerstitial nephritis