Main description:

This book brings together specialist authors from a variety of medical disciplines to give comprehensive coverage of the whole spectrum of women's vascular health. Covering coronary artery disease and its precursors, venous disease, thrombophilic defects, hormonal therapy and haemorrhagic problems, the content is divided into three sections.

Section one reviews generic issues including the pathophysiology of arteriosclerosis, metabolic factors in vascular disease, the epidemiology and management of CHD in women. The management of cardiac syndrome X and the problem of diabetes are also discussed here. The second section looks at women's vascular health as it applies to fertility issues and during pregnancy such as polycystic ovarian disease, menstrual dysfunction, the menopause, venous thromboembolism and haemorrhagic problems. In the concluding third section, hormonal therapy in women and in particular the oral contraceptive pill and hormone replacement therapies are covered.

The reader will be given a clear overview of the potential mechanisms whereby such therapy can act as a risk factor for arterial and venous disease, and will receive clear guidance regarding prescribing.

Contents:

SECTION 1: OVERVIEW
1. Epidemiology of vascular disease in women
2. Pathophysiology of arterioscleriosis
3. Metabolic risk factors for vascular disease in women
4. Genetic factors in vascular disease
5. Diabetes mellitus in women
6. Haemostatic factors in vascular disease
7. Congenital Thrombophilia and Venous Disease
8. Acquired thrombophilia
9. Congenital and acquired haemorrhagic problems
10. The Vasculitides
11. Anticoagulants / anticoagulants in pregnancy
12. Antiplatelet agents
13. Prophylaxis of venous and arterial thromboembolism in medical and surgical patients
14. Management of coronary artery disease including syndrome X in women
15. Peripheral vascular disease in women
16. Cerebrovascular disease
17. Cancer and thrombosis in women
18. Management of DVT and PTE including longterm sequelae
SECTION 2: REPRODUCTIVE PROBLEMS
19. Irregular menstrual bleeding
20. Polycystic ovarian syndrome and vascular disease
21. The effect of pregnancy on the haemostatic and metabolic systems
22. Venous thrombosis in pregnancy
23. Venous thrombosis and ovarian stimulation
24. Thrombophilia and pregnancy complications
25. Heart disease in pregnancy
26. Hypertension, pre-eclampsia and intrauterine growth restriction
27. Thrombocytopenia in Pregnancy
28. Gestational diabetes
29. Maternal & fetal programming
SECTION 3: HORMONAL THERAPY IN WOMEN
30. Epidemiology of the combined oral contraceptive pill and thrombosis
31. The oral contraceptive pill, mechanisms of vascular risk and practical prescribing strategies for women with thrombotic problems
32. Epidemiology of HRT and vascular disease
33. Hormone replacement therapy and mechanism of vascular risk
34. Practical strategies for HRT prescribing