Main description:

This book presents a multispecialty and multidisciplinary approach on Amyloidosis and Fabry disease. These two "rare" diseases are underdiagnosed and have systemic peculiarities that should be emphasized for diagnosis. In both cases, early diagnosis is important for initiating treatment sooner, achieving better prognosis, and improving patients' quality of life.

The history of these patients, in general, involves a long journey among health professionals to obtain a diagnosis. Even after a patient is diagnosed, there are still difficulties in understanding these complex diseases, managing complications, and defining specific treatment. Therefore, this work will be a valuable resource for many healthcare professionals, including physicians of various specialties, nurses, physiotherapists, and medical students. It will also be of interest to patients who would like to understand Amyloidosis and Fabry disease.

The content will give healthcare professionals a clinical perspective and provide insights on proper care. Readers will be able to recognize the symptoms related to each disease and will be guided during diagnosis and treatment. Chapters include an overview on clinical course, and will address neurological, ophthalmological, dermatological, gastrointestinal, hematological and cardiology manifestations, orthopedic care, mutations, expressiveness according to epigenetics and multidisciplinary treatment. Chapter authors from around the world will contribute sharing their experience in managing these diseases.

Contents:

Part I - Amyloidosis

1. Description and Purposes: An Overview

2. Neurological Manifestations

3. Dysautonomy

4. Cardiology Manifestations

5. Syncope, Arrhythmia and Cardiac Devices

6. Urological and Kidney manifestations

7. Ophthalmological and Dermatological Manifestations

8. Gastrointestinal Symptoms

9. Hematological Associations

10. Orthopedic Care

11. Association of Neoplasms

12. Diagnostic tools

13. Genetics and Epigenetics

14. Treatment

Part II - Fabry Disease

15. Clinical Course: An Overview

16. Neurological Manifestations

17. Cardiology Manifestations

18. Kidney manifestations

19. Ophthalmological and Dermatological Manifestations

20. Gastrointestinal Symptoms

21. Diagnostic tools

22. Genetics

23. Treatment

Part III - Amyloidosis and Fabry Disease

24. Pathology and Differential Diagnosis

25. Clinical Research

26. The Role of Nursing in Chronic Patient's Care

27. Chronic Pain and Quality of Life