Main description:

This book talks about the multidimensional biological etiology of Alzheimer's disease and autism spectrum disorder which leads to distinctive ways of perception, thinking and learning in affected individuals. It provides a deeper emphasis on the need for early diagnosis, continuous assessment of patients and the proper educational methods and environment required towards enabling people affected with these disorders capable of evolving and learning.

This book explores alternative solutions for autism spectrum disorder based on the theory of brain plasticity, the relationship between the gut microbiota and the central nervous system along with genetic factors and toxic metal exposures which are responsible for the oxidative damage resulting in a decreased ability of the patients to use objects or response to auditory stimuli. It also identifies and provides the latest research towards dealing with memory loss, which is the first sign of cognitive impairment followed by behavioral disturbances. These symptoms are associated with a rigorous neuronal decline and the appearance of two brain lesions, senile plaques and neurofibrillary tangles, which are mainly composed of A and hyper phosphorylated tau protein respectively. This book also provides the latest research towards reducing autism disorder severity such as targeting the disease with symptomatic treatments such as cholinesterase inhibitors, NMDA receptor antagonist, -secretase and -secretase inhibitors, -secretase stimulators, tau inhibitors, immunotherapy, nutraceuticals, and nano drugs.

This book will not only be a good resource for professors and lecturers teaching in the area of neuroscience, medicine, biochemistry, neuroinformatics, and nanotechnology, etc. but also for professionals working in the field of occupational therapy and geriatric clinics and rehabilitation.

Contents:

1) The role of mitochondria in neurodegeneration2) Brain region volumes in neurodegeneration3) Brain-computer interface applications in neurodegeneration4) Cognitive applications and tests in neurodegeneration5) Computerized tomography in assessment of neurodegeneration6) Frailty indexed systems in neurodegeneration7) Magnetic resonance imaging (MRI) in assessment of neurodegeneration8) Medical decision support systems in neurodegeneration9) SPECT perfusion imaging in assessment of neurodegeneration10) The use of cerebrospinal fluid in the diagnosis of neurodegeneration11) Animal-assisted therapy in neurodegeneration12) Cholinesterase inhibitors and NMDA receptor antagonists in neurodegeneration13) Cognitive Impairment and Rehabilitation14) Depression and Psychotic symptoms in neurodegeneration15) Environmental enrichment for multisensory Stimulation in neurodegeneration16) Immunotherapy in neurodegeneration17) Mediterranean diet in neurodegeneration18) Nanotechnological applications in diagnosis and treatment of neurodegeneration19) Natural products as promising drug candidates for neurodegeneration20) Sleep in neurodegeneration21) Health Economics and management of neurodegeneration22) Health tourism in neurodegeneration23) Transcranial direct current stimulation in ASD and ADEthical, Legal and Social Implications24) Biobanks, Big Data and Data Sharing in ASD and AD25) Failed clinical trials in ASD and AD26) Gene Editing, CRISPR and human enhancements in ASD and AD27) Health Economics and Management of ASD and AD 28) Health Tourism in ASD and AD29) Implementation of precision Medicine in ASD and AD30) Next-Generation Ethics and IRB in ASD and AD31) Preparing professionals for ASD and AD