Main description:

Coronaviruses can cause illness, severe disease, and death; e.g. Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), and COVID-19. Vaccine development and antiviral drugs are challenged by the propensity for viral mutations allowing these viruses to evade such therapies. There are a number of bioactive compounds from natural sources, which can exert health benefits and act as antiviral therapies such as anti-inflammation, anti-oxidative stress, and immune regulation. This book summarizes research on the potential efficacy and underlying mechanisms of bioactive compounds and traditional medicines against SARS-CoV-2.

Key Features

Summarizes the potential benefits of bioactive therapies for coronaviruses.

Focuses on COVID-19, but also covers MERS and SARS.

Provides alternatives to vaccines and other antiviral drugs whose efficacy is reduced by viral mutations.

Relevant for clinicians and public health officials.

Contents:

Chapter 1 - Omics-guided intervention strategies in combatting SARS-CoV-2: Recent advancements and challenges

Chapter 2 - The application of computer-aided drug design methods for developing natural compounds-based therapeutics against SARS-CoV-2

Chapter 3 - Therapeutic targets of host factors for potential COVID-19 treatments

Chapter 4 - Phytocompounds: A paradigm shift as therapeutics for COVID-19

Chapter 5 - Flavonoids as potential therapeutic agents against the SARS-CoV-2 infection: An overview

Chapter 6 - Antiviral activities of flavonoids against COVID-19 and other virus-causing ailments

Chapter 7 - Potential therapeutic effects of flavonoids against the COVID-19 infection: The mode of action

Chapter 8 - Terpene and Terpenoid: Potent antiviral agents against SARS-CoV-2

Chapter 9 - Phytonutrients and secondary metabolites to cease SARS-CoV-2 loop

Chapter 10 - Treatment strategies against COVID-19 using bioactive compounds and plant secondary metabolites

Chapter 11 - The potential contribution of vitamin K as a nutraceutical to scale down the mortality rate of COVID-19

Chapter 12 - Gastrointestinal Symptoms in COVID-19 patients: Prevention and Treatment

Chapter 13 - Mechanisms and management options of liver injury in COVID19: A Review

Chapter 14 - Marine species-derived bioactives against coronavirus disease

Chapter 15 - Potential bioactive compounds of Indian flora against SARS-CoV-2

Chapter 16 - Natural product-derived active compounds for the management of COVID-19: A summary from Indochina

Chapter 17 - Novel therapeutic strategy based on nanomedicine targeting thrombosis for SARSCoV-2

Chapter 18 - Nanomaterials in combating human coronavirus infections

Chapter 19 - Structural insights into drug targets from MERS, SARS-CoV, and SARS-CoV-2 and scope for phytochemicals as broad-spectrum anti-virals and immunomodulators.

Chapter 20 - Precision phytochemicals for COVID-19-induced olfactory dysfunction