Main description:

This handbook systematically presents biomarkers for traumatic injuries. The book covers topics such as traumatic brain injury, liver injury, burn severity, muscle heart damage, and acute inflammation in polytrauma and their detection by biomarkers.

Biomarkers and methods used in critical care and critically ill patients are discussed, as well as biomarkers in trauma and special conditions. Specific biomarker components are explained and models for modeling trauma in research are presented.

This systematic handbook is an excellent resource for researchers and specialists in trauma research and treatment, as well as clinicians and physicians who want a thorough overview of various injuries, trauma, and their detection methods.

Contents:

Biomarkers and outcomes: the example of traumatic brain injury.- Biomarkers in neurological injury: fibrinogen and beyond.- Biomarkers for liver injury: micro RNAS and beyond.- Biomarkers in muscle injury: proteomic and beyond.- Biomarkers in lung injury:.- Biomarkers and penetrating thoracic trauma.- Biomarkers in renal injury.- Biomarkers of heart muscle damage and injury: mRNA expression and beyond.- Biomarkers of burn severity.- Biomarkers and prognosis in sepsis: muscle mass and beyond.- Biomarkers of acute inflammation in polytrauma.- Electrolytes in critical care as a biomarker.- Critical care and 5'-Aminolevulinate synthase 2 (ALAS2) expression as a biomarker.- miRNAs as biomarkers of critically Ill patients.- C-Reactive protein and implications to the Neonatal Intensive Care Unit.- 129Xe magnetic resonance imaging (MRI) as a biomarker and implications for critical care.- Gas imaging of aeration and fractional ventilation as a biomarker in critical care.- Circulating PD-1/2B4 CD8+ T-cells patterns as biomarkers and the ICU.- Collagen and fibrotic biomarkers in critical care.- Biomarker mortality prediction model for sepsis in critical care: parsimonious modelling and beyond.- Acute kidney injury in critical care and biomarkers.- Platelet Function Assays in trauma.- Coagulation tests and fibrinogen concentrate in trauma.- Biomarkers and the time window-in trauma patients.- Inflammatory biomarkers in animal model of brain Injury