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MORE ABOUT THIS BOOK
Main description:
This book functions as a comprehensive and authoritative reference book in blood transfusion and blood substitutes. It is a collection of the latest developments and the newest investigations, and individual chapters are written by world experts in the arena.
The book begins with a historical review on the practice of transfusions as well as the components and physiology of blood. The following chapters cover various topics, including platelet substitutes, hemoglobin-based oxygen carriers, perfluorocarbon based oxygen carriers, and safety issues related to artificial hemoglobin. All chapters provide a bulleted highlights list to facilitate readers in mastering the main points of each individual chapter.
Blood Substitutes and Oxygen Biotherapeutics is an invaluable reference book for perioperative care providers, hematologists, anesthesiologists, surgeons, obstetricians and gynecologists.
Contents:
Chapter
Section I Transfusion: Science and Practice
1
ERYTHROCYTE TRANSFUSION: BRIEF HISTORY AND CURRENT PRACTICE
2
ATP and Oxygen: the Energy Economy of the Cell
3
Physiological Functions of Blood
4
Hemoglobin: Physiology and Hemoglobinopathy
5
The Global Burden of Anemia
6
Blood Component Therapy: the History, Efficacy, and Adverse Effects in Clinical Practice
7
Allogeneic Blood Transfusion: Complications and Side Effects
8
THE REAL-TIME EFFECTS OF ARTIFICIAL BLOOD SUBSTITUTES ON THE MICROCIRCULATION
9
Vascular endothelium and nitric oxide
10
A Brief History of Development of Nanobiotechnology-based Blood Substitutes
Section II Pharmacology and Physiology of Oxygen Therapeutics
11
Classification of Blood Substitutes
12
Hemoglobin-based Oxygen Carriers: Brief History, Pharmacology and Design Strategies, Review of the Major Products in Failed Clinical Trials, On-Going Studies, and Coagulation Concerns.
13
Complications of HBOCs including clinical safety issues
14
Free Hemoglobin Toxicity
15
Nanotechnology-based oxygen and drug carriers
16
Perfluorocarbon-based Oxygen Carriers LSU team will work on it
17
Platelet Substitutes
18
Plasma Substitutes: Synthetic Colloid and Renal Toxicity
Section III Products in Development
19
Novel nanobiotherapeutic based blood substitutes
20
Paradigm Shift for Designing Oxygen Therapeutics: New Insights Emerging from Studies with Transgenic Mouse Models of Sickle Cell Disease
21
Hemoglobin-Based Blood Substitute With Pharmacological Activities of ATP, Adenosine and Glutathione: A Review of Preclinical and Early Clinical Experience
22
Hemoglobin vesicles as artificial red cells
23
Low Volume Resuscitation Agents in Prehospital Medicine needs bullets needs modification
24
ErythroMer: Bio-Inspired Artificial Red Blood Cell
25
OxyVita: History, Studies, and Future
26
Erythrocruorin as a novel blood substitute
Section IV Products, not Approved, in Progress, and Approved for Human/Veterinary Use
27
HemAssist: History, clinical trials and lessons learned
28
Development of Recombinant Hemoglobin-Based Oxygen Carriers-Somatogen: Studies and Lessons Learned
29
Hemolink: History, Clinical Trials and Lessons Learned
30
PolyHeme: History, Clinical Trials, and Lessons Learned
31
Clinical Evaluation of MP4CO: A Phase 1b Escalating-Dose, Safety and Tolerability Study (OLD CH3)
in Stable Adult Patients with Sickle Cell disease
32
Oxygent: A Perfluorochemical-based Oxygen Therapeutic for Surgical Patients
33
Sanguinate: History and clinical evaluation of a multi-modal HBOCs Bryan Romito
34
M101, the Hemoglobin from the Sea: History and Therapeutic Perspectives
35
Hemopure: clinical trials and current status
36
Perftoran: History, Studies, Approval and Use in Russia, and Moving Forward Henry will review it offering a college student to review it?
37
Oxycyte
38
Hemoximer
Section V Specific Indications, Regulatory Issues and Future Directions
39
Transplantation and Hemoglobin-based O2 Carriers by end of April
40
Hemorrhagic Shock: Role for Oxygen Therapeutics in Military and Civilian Trauma, early June
41
HBOCs in Trauma
42
Use of Oxygen Therapeutics in Patients for Whom Blood is Not an Option, and Moving Forward wait for several weeks to Mid-late April
43
Regulatory Update: How to Get an Oxygen Therapeutic Approved for Clinical Use
PRODUCT DETAILS
Publisher: Springer (Springer Nature Switzerland AG)
Publication date: August, 2022
Pages: None
Weight: 1587g
Availability: Available
Subcategories: Anaesthetics and Pain, General, Haematology