Published July, 2014
By Martin Lorenz Stein
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
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Martin Stein's thesis describes a novel methodology for natural product discovery. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens.

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Published July, 2014
By Ismail Adeniran
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
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The Short QT Syndrome (SQTS) is characterized by abbreviated QT intervals on the electrocardiogram, increased risk of cardiac arrhythmias and sudden death.

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Published June, 2014
By Sara Bobone
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
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In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria.

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Published June, 2014
By Adi Haber
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Springer Theses
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Adi Haber's thesis summarises the use of a new entity, the corrole, to combat one of the major cardiovascular diseases, atherosclerosis. These results will pave the way for ongoing regulated preclinical studies focussed on the development of metallocorroles as potential drugs for treating cardiovascular diseases.

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Published June, 2014
By Marvin Jens
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
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The introduction presents post-transcriptional gene regulation from a distinct angle, highlighting aspects of information theory and evolution and laying the groundwork for the questions addressed in the subsequent chapters, which concern the regulation of the transcriptome as the primary functional carrier of active genetic information.

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Published May, 2014
By Jing Yu
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
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The results in this thesis show that Dopa plays an essential role in mussel adhesion and that mussels delicately control the interfacial redox environment to achieve strong and durable Dopa mediated adhesion.

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Published May, 2014
By Nicola Salvi
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
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Nicola Salvi's thesis offers a remarkably cogent view of highly sophisticated NMR methods. Salvi developed these methods in order to characterize the amplitudes and frequency ranges of local motions in biomolecules such as proteins.

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Published May, 2014
By Hua Zhang
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Springer Theses
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From a new perspective, namely focusing on the interaction of selenium and mercury, this thesis provides new insights into traditional research on biogeochemical cycles of mercury in soil-plant interaction and associated human exposure and risks.

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Published April, 2014
By Margarita Puentes Vargas
Publisher: Springer (Springer International Publishing AG)
Series: Springer Theses
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This book presents an innovative concept for the realization of sensors based on a planar metamaterial microwave array and shows their application in biomedical analysis and treatment.

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Published March, 2014
By Jianxian Gong
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Springer Theses
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In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton.

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