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MORE ABOUT THIS BOOK
Main description:
Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.
Contents:
Part I. Genes and Polymorphisms in Cardiovascular Disease
Angiotensin II Receptor Polymorphisms and Hypertension
Bruno Baudin
Angiotensinogen Gene Polymorphisms and Hypertension
Ashok Kumar
Substitution Mapping: Using Congenic Strains to Detect Genes Controlling Blood Pressure
Bina Joe and Michael R. Garrett
Local Production of Angiotensinogen: Insights From Genetic Manipulation of Mice
Kamal Rahmouni and Curt D. Sigmund
Cardiovascular Pharmacogenomics
Julie A. Johnson and Larisa H. Cavallari
Genetic Polymorphisms and Response to HMG-CoA Reductase Inhibitors
Anke-Hilse Maitland-van der Zee, Olaf H. Klungel, and Anthonius de Boer
Monogenic Causes of Heart Failure: Familial Dilated Cardiomyopathy
Hideko Kasahara
Part II. Gene Transfer for Combating Cardiovascular Disease
Gene Therapy vs Pharmacotherapy
Ryuichi Morishita
Molecular Therapeutic Approaches for Myocardial Protection
Alok S. Pachori, Luis G. Melo, and Victor J. Dzau
Gene Transfer and the Cardiovascular System
William H. Miller, Stuart A. Nicklin, Andrew H. Baker, and Anna F. Dominiczak
Kallikrein Gene Transfer in Hypertension, Cardiovascular and Renal Disease, and Stroke
Julie Chao and Lee Chao
Current and Future Novel Targets of Gene Therapy for Hypertension
Michael J. Katovich, Justin L. Grobe, and Mohan K. Raizada
Application of Viral Gene Transfer in Studies of Neurogenic Hypertension
Sergey Kasparov, A. G. Teschemacher, and Julian F. R. Paton
Vigilant Vectors: Intelligent Gene Vectors for Cardioprotection in Myocardial Ischemia
M. Ian Phillips and Yi Tang
Gene Therapy for Cerebral Arterial Diseases
Yoshimasa Watanabe and Donald D. Heistad
Part III. Regenerative Tissues for the Diseased Cardiovascular System
Therapeutic Angiogenesis and Vasculogenesis for Tissue Regeneration
Paolo Madeddu
Cell Transplantation: The New Frontier
Shafie Fazel, Paul W. M. Fedak, Richard D. Weisel, Denis Angoulvant, Terrence M. Yau, and Ren-Ke Li
Embryonic Stem Cells and the Cardiovascular System
Neta Lavon and Nissim Benvenisty
Index
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: December, 2010
Pages: 376
Weight: 714g
Availability: Available
Subcategories: Cardiovascular Medicine
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