Main description:

Case Studies in Immunology, Sixth Edition, presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. The case histories illustrate essential points about the mechanisms of immunity and describe immunological problems seen in the clinic. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. Case Studies in Immunology highlights major common disorders of immunity, including hypersensitivity types I-IV, immune deficiencies, and autoimmune disorders. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the specific disorders. An end-of-case summary, questions, and discussion points conclude each case. Case Studies in Immunology can be used as a stand-alone book, or as a clinical companion alongside Janeway's Immunobiology, Eighth Edition. A marginal icon in Janeway's Immunobiology provides the reader with a link to the relevant Case Study, where the science is applied in a clinical setting. The book includes a total of 53 cases.
The Sixth Edition is extensively revised and updated and includes ten new cases: DiGeorge Syndrome Hemophagocytic Lymphohistiocytosis Chediak-Higashi Syndrome Hyper IgE Syndrome Ataxia Telangiectasia Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome Severe Congenital Neutropenia Recurrent Herpes Simplex Encephalitis Systemic Onset Juvenile Idiopathic Arthritis Crohn's Disease

Contents:

Case 1 X-linked Agammaglobulinemia Case 2 CD40 Ligand Deficiency Case 3 Activation-induced Cytidine Deaminase Deficiency Case 4 Common Variable Immunodeficiency Case 5 X-linked Severe Combined Immunodeficiency Case 6 Adenosine Deaminase Deficiency Case 7 Omenn Syndrome Case 8 MHC Class II Deficiency Case 9 DiGeorge Syndrome Case 10 Acquired Immune Deficiency Syndrome (AIDS) Case 11 Graft-Versus-Host Disease Case 12 MHC Class I Deficiency Case 13 X-linked Lymphoproliferative Syndrome Case 14 Hemophagocytic Lymphohistiocytosis Case 15 Chediak-Higashi Syndrome Case 16 Wiskott-Aldrich Syndrome Case 17 Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Case 18 Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease Case 19 Autoimmune Lymphoproliferative Syndrome (ALPS) Case 20 Hyper IgE Syndrome Case 21 Ataxia Telangiectasia Case 22 Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome Case 23 X-linked Hypohidrotic Ectodermal Dysplasia and Immunodeficiency Case 24 Interferon-I Receptor Deficiency Case 25 Severe Congenital Neutropenia Case 26 Chronic Granulomatous Disease Case 27 Leukocyte Adhesion Deficiency Case 28 Recurrent Herpes Simplex Encephalitis Case 29 Interleukin 1 Receptor-associated Kinase 4 Deficiency Case 30 Congenital Asplenia Case 31 Hereditary Angioedema Case 32 Factor I Deficiency Case 33 Deficiency of the C8 Complement Component Case 34 Hereditary Periodic Fever Syndromes Case 35 Systemic Onset Juvenile Idiopathic Arthritis Case 36 Rheumatoid Arthritis Case 37 Systemic Lupus Erythematosus Case 38 Mixed Essential Cryoglobulinemia Case 39 Crohn's Disease Case 40 Multiple Sclerosis Case 41 Autoimmune Hemolytic Anemia Case 42 Myasthenia Gravis Case 43 Pemphigus Vulgaris Case 44 Celiac Disease Case 45 Acute Infectious Mononucleosis Case 46 Hemolytic Disease of the Newborn Case 47 Toxic Shock Syndrome Case 48 Lepromatous Leprosy Case 49 Acute Systemic Anaphylaxis Case 50 Allergic Asthma Case 51 Atopic Dermatitis Case 52 Drug-induced Serum Sickness Case 53 Contact Sensitivity to Poison Ivy Answers Figure Acknowledgments Index