Main description:

A concise clinical reference that facilitates the diagnosis of intrauterine and perinatally acquired infections was the goal in creating the Congenital and Perinatal Infections: A Concise Guide to Diagnosis. Information about the natural history, m- agement, and outcome of these infections is well detailed in many other sources and so has not been included. Rather, the focus of the book is diagnosis. The initial chapters provide general information about serological and nonserological assays that are used for the diagnosis of infections, and a chapter about the placenta includes details about histopathological findings that can be helpful with the diagnosis of congenital inf- tions. The remainder of the book is devoted to the diagnosis of specific congenital and/ or perinatal infections. As illustrated in the chapters about specific infections, the approach to diagnosis of a congenital or perinatally acquired infection in the neonate begins, when possible, with consideration and diagnosis of infection in the pregnant woman, knowledge of how the infection is transmitted, and the risk of that infection for the woman and her fetus or neonate. The possibility of congenital or perinatal infection in neonates is usually considered because of the diagnosis of, or concern about a s- cific infection in, a mother during pregnancy that can be transmitted to the neonate or because of clinical findings in the neonate at birth that suggest an infectious cause.

Contents:

Part I. The Tools of Diagnosis

Diagnostic Assays: Serology
William Borkowsky

Nonserologic Assays for Detection of Bacteria and Other Nonviral Infections
Timothy J. Cleary

Diagnosis of Viral Infections by Viral Isolation and Identification or by Direct Detection
David Schnurr

Placental Histopathology
Edwina J. Popek

Part II. Diagnosis of Specific Infections

Herpes Simplex Virus
David W. Kimberlin

Cytomegalovirus
Suresh B. Boppana

Epstein-Barr Virus
Suresh B. Boppana

Varicella-Zoster Virus
Anne A. Gershon

Human Herpesviruses 6 and 7
Charles T. Leach

Human Herpesvirus 8
Charles Wood and Charles D. Mitchell

Rubella
Cecelia Hutto

Parvovirus B19
Mobeen H. Rathore

Enteroviruses
Mark J. Abzug

Human Immunodeficiency Virus Type 1
David Berman and Gwendolyn B. Scott

Hepatitis Viruses
Ravi Jhaveri and Yvonne Bryson

Lymphocytic Choriomeningitis Virus
Kevin A. Cassady

Dengue Virus
Enid J. Garcia-Rivera and Jose G. Rigau-Perez

Syphilis
Sithembiso Velaphi and Pablo J. Sanchez

Group B Streptococcus
Cecelia Hutto

Listeria monocytogenes, Neisseria gonorrhoeae, and Other Bacteria
Katherine M. Knapp

Mycobacterium tuberculosis
Kim Connelly Smith and Jeffrey R. Starke

Toxoplasma gondii
Aida Chaparro and Charles D. Mitchell

Chlamydia trachomatis
Margaret R. Hammerschlag

Mycoplasma and Ureaplasma
Ken B. Waites

Candida
Patricia Whitley-Williams

Malaria
Masako Shimamura

Index