Main description:

This book provides a comprehensive, state-of-the-art overview of cholangiocarcinoma (CCA). The text is structured to effectively present a broad yet concise overview of bile duct cancer, its relevant definitions, classification schemata, clinical management tenets, translational (including molecular and cellular) facets, and future directions. The book features numerous high-yield illustrations and is authored by an eclectic range of renowned experts in various areas of CCA, reflecting the multidisciplinary nature of the field.
Filling a critical gap in the field, Diagnosis and Management of Cholangiocarcinoma: A Multidisciplinary Approach is a valuable resource for clinicians and practitioners who treat patients with bile duct cancer.

Contents:

Preface and Acknowledgement

I. Anatomy and histology of the biliary tree and cholangiocarcinoma

Anatomy of the Biliary Tree: Normal, Anomalous, and Relationship to Cholangiocarcinoma
Anatomic and Morphologic Classifications of Cholangiocarcinoma
Intraductal tumors of the biliary tract: Precursor lesions and variants
Pathologic Basis and Classification of Biliary Epithelial Neoplasms II. Diagnosis and management of cholangiocarcinoma
Clinical epidemiology of cholangiocarcinoma
Biochemical indicators of Cholangiocarcinoma
Imaging of Cholangiocarcinoma
Pathological diagnosis of cholangiocarcinoma
Challenges in diagnosing cholangiocarcinoma: pulling together biochemical, radiological, and cytopathological data
PSC-Associated Cholangiocarcinoma: Diagnostic And Therapeutic Considerations
Fluke-associated Cholangiocarcinoma: a regional epidemic
Endoscopic Management of Cholangiocarcinoma
The Role of Endoscopic Ultrasound in Cholangiocarcinoma
Surgical approach to the treatment of cholangiocarcinoma
Liver Transplantation for Cholangiocarcinoma
Neoadjuvant and Adjuvant Therapy for Cholangiocarcinoma
Palliative chemotherapy and radiotherapy for cholangiocarcinoma
Interventional Radiology Therapies for Intrahepatic Cholangiocarcinoma
Established and emerging biomarkers for prediction, early detection, and prognostication of cholangiocarcinoma
Cholangiocarcinoma Surveillance in Primary Sclerosing Cholangitis and IgG4-related sclerosing cholangitis
Novel targeted therapies in clinical use and on the horizon for cholangiocarcinoma III. Experimental and translational facets of cholangiocarcinoma
In vitro and in vivo model systems of cholangiocarcinoma
Organoid models of Cholangiocarcinoma
The tumor environment: cholangiocarcinoma-associated fibroblasts and beyond
Glycosylation in cholangiocarcinoma development and metastasis: diagnostic and therapeutic considerations
The investigative therapeutic pipeline for cholangiocarcinoma: insights from model systems