Main description:

Advances in cancer therapy and transplantation are increasing the numbers of immunocompromised patients throughout the world. This comprehensive review presents state-of-the-art diagnostics for infectious complications in the immunocompromised patients. Providing complementary views of often complex diagnostic challenges, the new edition presents topics such as host biology and antineoplastic and transplantation techniques; the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression; the approach, interpretation, and limitations of the laboratory diagnosis of infections caused by a wide range of etiologic agents; laboratory diagnosis of infections of organ systems, such as respiratory tract, gastrointestinal tract, and central nervous system; and, diagnostic aspects of prosthetic devices and catheters, healthcare-acquired infections, and morphologic considerations (anatomic pathology). New sections discuss tissue pathology, HIV, hepatitis viruses, papilloma and polyoma viruses, and aerobic and anaerobic bacteriology. This book will inform laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of patients who are immunocompromised.

Strategies for providing optimal care to this high-risk patient group.
The immunocompromised patient population is increasing throughout the world. Major advances in transplantation techniques have expanded access to lifesaving therapies and improved outcomes in these high-risk populations. An understanding of the biology of these infections, host conditions, and the limitations of technologies used to detect and quantify such pathogens is critical to optimal care.
This new edition of Diagnostic Microbiology of the Immunocompromised Host covers all aspects of state-of-the-art diagnostics for infectious complications in the immunocompromised patient. Editors Randall Hayden, Karen Carroll, Yi-Wei Tang and Donna Wolk, assembled the contributions of a team of preeminent authors to discuss a broad range of topics, including
* relevant aspects of host biology, antineoplastic, and transplantation techniques and the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression
* approaches, interpretations, and limitations of laboratory diagnosis of infections by a wide range of specific etiologic agents
* laboratory diagnosis of infections of specific organ systems, such as respiratory tract infections, gastrointestinal tract infections, and central nervous system infections
* special topics such as prosthetic devices and catheters, healthcare acquired infections, and morphologic considerations (anatomic pathology)
* future diagnostic technologies and their potential impact on the field
Diagnostic Microbiology of the Immunocompromised Host is a resource for laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of the immunocompromised host.

Contents:

Contents

Contributors
Preface
Foreword

I. OVERVIEW OF INFECTIONS IN THE IMMUNOCOMPROMISED HOST

1. Overview of Infections in the Immunocompromised Host
Lesia K. Dropulic and Howard M. Lederman

II. LABORATORY DIAGNOSIS: APPROACHES, INTERPRETATIONS, AND LIMITATIONS
INFECTIONS BY SPECIFIC ETIOLOGIC AGENTS

2. Human Immunodeficiency Virus
Wendy S. Armstrong, Jeannette Guarner, Colleen S. Kraft, and Angela M. Caliendo

3. Chronic Hepatitis B, C, and D
Bryan R. Cobb and Alexandra Valsamakis

4. Cytomegalovirus
M. Veronica Dioverti and Raymund R. Razonable

5. Epstein-Barr Virus
Andrew Nowalk and Michael Green

6. Herpes Simplex Virus and Varicella-Zoster Virus
Myron J. Levin, Adriana Weinberg, and D. Scott Schmid

7. Human Herpesviruses 6A, 6B and 7
Henri Agut, Pascale Bonnafous, and Agnes Gautheret-Dejean

8. Human Papillomavirus
Eileen M. Burd and Christina L. Dean

9. Polyomaviruses
Linda Cook

10. Adenovirus
Michael G. Ison and Randall T. Hayden

11. Respiratory RNA Viruses
Richard L. Hodinka

12. Enteroviruses and Parechoviruses
James J. Dunn

13. Parvovirus B19
Marie Louise Landry

14. Filamentous Fungi
Margaret V. Powers-Fletcher, Brian A. Kendall, Allen T. Griffin, and Kimberly E. Hanson

15. Yeasts
Sean X. Zhang and Nathan P. Wiederhold

16. Mycobacteria
Patricia J. Simner, Gail L. Woods, and Nancy L. Wengenack

17. Aerobic Actinomycetes of Clinical Significance
A. Brian Mochon, Den Sussland, and Michael A. Saubolle

18. Parasites
Elitza S. Theel and Bobbi S. Pritt

19. Selected Topics in Aerobic Bacteriology
Geraldine Hall and Karen C. Carroll

20. Selected Topics in Anaerobic Bacteriology
Deirdre L. Church

III. LABORATORY DIAGNOSIS: APPROACHES, INTERPRETATIONS AND LIMITATIONS
INFECTIONS OF SPECIFIC ORGAN SYSTEMS

21. Lower Respiratory Tract Infections
Karen C. Carroll and La'Tonzia L. Adams

22. Genitourinary Tract Infections
Odaliz Abreu Lanfranco and George J. Alangaden

23. Gastrointestinal Infections
Kevin Alby and Irving Nachamkin

24. Central Nervous System Infections
Andrea J. Zimmer, Victoria E. Burke, and Karen C. Bloch

25. Bloodstream Infections
Donna M. Wolk, Raquel M. Martinez, and Diana R. Hernandez

26. Skin and Soft Tissue Infections
Anne Spichler Moffarah, Mayar Al Mohajer, Bonnie L. Hurwitz, and David G. Armstrong

IV. SPECIAL TOPICS

27. Prosthetic Device Infections
Raquel M. Martinez, Thomas R. Bowen, and Michael A. Foltzer

28. Hospital-Associated Infections
Esther Babady

29. Surgical Pathologic Diagnosis
Mary K. Klassen-Fischer and Ronald C. Neafie

Index