Main description:

Down syndrome remains the most common recognisable form of intellectual disability. The challenge for doctors today is how to capture the rapidly expanding body of scientific knowledge and devise models of care to meet the needs of individuals and their families. Down syndrome; Clinical Perspectives provides doctors and other health professionals with the information they need to address the challenges that can present in the management of syndrome. Chapters written by internationally respected paediatricians with a special interest in Down syndrome, cover Down syndrome comorbidities, such hearing problems, gastrointestinal disorders, congenital heart diseases, as well as the underlying biology and new developments in molecular genetics. Contributions from the UK Down Syndrome Association and Down Syndrome Medical Interest Group define how doctors can work effectively with other professionals to improve health care provisions for this group. Each chapter is illustrated by informative case scenarios and answers to FAQs from parents and carers.

Contents:

Contents List 1. Introduction Richard W Newton 2. Advances in molecular biology Arjan Bouman and Raoul Hennekam 3. Antenatal diagnosis Shiela Puri and Joan Morris 4. Life for a person with DS Stuart Mills, Gillian Bird, Lesley Black, Vanda Ridley, Sheila Heslam and Lou Marsden with Claire McCall and Fiona Straw 5. Hearing issues Emma McNeill, Patrick Sheehan and Liz Marder 6. Vision and eye disorders Pat Charleton and Maggie Woodhouse 7. Immune function, infection and autoimmunity Peter Arkwright and Liz McDermott 8. Cardiovascular Disease Robert Tulloh, Emma Pascall and Natali Chung 9. Respiratory diseases Hazel Evans, Katy Pike, Marian McGowan and Sally Shott 10. Growth Jennifer Dennis 11. Endocrine disorders Malcolm Donaldson and Kath Leyland 12. Haematological disorders Rebecca James and Shiela Puri 13. Gastrointestinal disorders Patricia D Jackson, Peter Gillett and Sarah Almond 14. Renal and urinary tract abnormalities Christine Hardie and Rajiv Puri 15. Musculoskeletal manifestations of Down syndrome Janet Gardner-Medwin, Maureen Todd, Sally Tennant and Shiela Puri 16. Dermatological manifestations Sheila M. Clark and Laura Savage 17. Impact for oral and dental Health Liz Marder and June Nunn 18a. Neurological disorders Richard W Newton 18b. Developmental, psychological and psychiatric function Jeremy Turk 18c. Mental health and dementia Tiina Annus, Liam Reese Wilson and Anthony Holland 19. Interventions and alternative therapies: medicine and myth Richard W Newton 20. Perpsectives Richard W Newton