Main description:

Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.

Contents:

A. Current status and active dynamics of AMR 1. Antimicrobials in livestock production and its cross-domain dynamicsBishwo Pokharel*, Sandeep Raj Karna2. Antibiotics and resistance in environmentRahil Changotra, Atul Chalotra, Himadri Rajput*3. Antimicrobials in agriculture and its implications in antimicrobial resistance Shweta Singh and Arun Goyal*4. Modern diagnostic tools for rapid detection of multidrug resistance Nimisha Tehri*, Saurabh Kadyan, Tejinder P. Singh, Piyush Tehri, Amit Vashishth 5. The Use of Antimicrobials in Agriculture and socio-economic considerations in global worldHimadri Rajput, Swati Dhiman, Rahil Changotra*6. Epidemology of microbial infections Kanika, Aneesh Ali, Md. Meraj Ansari, Rehan Khan*7. Socioeconomic impact of antimicrobial resistance and their integrated mitigation by One Health approach Md.Meraj Ansari, Kaushik Kuche, Rohan Ghadi, Tushar Date, Dasharath Chaudhari, Rehan Kha, Sanyog Jain* B. Mode of action of antimicrobials in mitigation of AMR 8. Regulations in antimicrobial drug development Challenges, and new incentives Sanjana Kumariya, Richa Mehra, Rashmi Kumariya*9. New Insights into and updates on antimicrobial agents Vagish Dwibedi, Santosh Kumar Rath*10. Polyphenols as emerging antimicrobial agents Ashraf Ali, Antonio Parisi, Giovanni Normanno*11. Antimicrobial peptides and small molecules as antibiotics substitute Nidhi Sethi*12. Molecular mechanisms of antimicrobial resistance in S. aureus biofilms Vanessa Silva, Jose L. Capelo, Gilberto Igrejas and Patricia Poeta*13. Antimicrobial resistance: meaning and developing realization Atul K. Chandu, Samsher Singh*, Santosh K Rath 14. Chemical diversity in fungi: strategies to mitigate antimicrobial resistance Neha Kapoor, Richa Bhardawaj and Lokesh Gambhir*15. Phage therapy as an alternative treatment in the fight against AMR: Real-world problems and possible futuresRajni Kaur, Nidhi Sethi*C. Novel strategies to combat AMR 16. Omics and in-silico approaches in the surveillance and monitoring of antimicrobial resistance Ajith M. Thomas, Lija L. Raju, S. Sudheer Khan*17. Antimicrobial activity of bioactive compounds (Thymoquinone & Eugenol) and its nanoformulations therapeutic potential. Jasmeet Kaur, Mohamad Taleuzzaman*, Iqra Rahat 18. Nanoparticles as a future alternative against multiple drug resistance Md.Meraj Ansari, Kaushik Kuche, Rohan Ghadi, Tushar Date, Dasharath Chaudhari, Faiyaz Ahmad Ansari, Rehan Khan, Akshay Vyawahare, Sanyog Jain* 19. Nano-cargos Boarded Defensins to Combat Multi-drug Resistance Saurabh Bhorkade, Pawan Kumar Pandey, Md. Meraj Ansari, Sanyog Jain*20. Implementation of nano-vehicles to disguise and fight multi-drug resistance Tharun K Bollu, Divya S Parimi, Chandra S Bhatt, Imran Uddin, Anil K Suresh* 21. Silver nanoparticles as potent multi-drug resistant in-corporants in biomedicine Imran Uddin, Divya S. Parimi, Tarun K. Bollu, Chandra S. Bhatt and Anil K. Suresh* 22. Role of gold nanoparticles against bacterial multidrug resistance (MDR): An emerging therapeutic revolution Kaushik Kumar Bharadwaj, Bijuli Rabha, Bhabesh Kumar Choudhury, Aditi Das, Lydia Islary, Dorothy Bhattacharjya, Monoswi Chakraborty, Debabrat Baishya, Arabinda Ghosh* 23. Carbon nanoparticles: A potential cost-effective approach to counter antimicrobial resistance Afroza Khanam* and Firdous Ahmad Khan 24. Antimicrobial interfaces as augmentative strategy against antimicrobial resistance Sunny Dholpuria*, Rohit Kumar, Niraj Kumar Jha, Shipra Jha, Sharad Agrawal 25. Nano- Strategies against rising Antimicrobial resistance (AMR) - Metallic Nanoparticles as Nano-weapon Purnima Sharmaa, Dinesh Goyal, and Bhupendra Chudasama*