Main description:

Low-Level Laser Therapy (LLLT) also known as photobiomodulation is almost 50 years old, and recently has been getting increasing acceptance from the scientific, medical, and veterinary communities. Discoveries are constantly being made about the cellular and molecular mechanisms of action, the range of diseases that can be treated is also rising, and home use LED devices are becoming common.

This book compiles cutting-edge contributions from the world's leading experts in Photobiomodulation and LLLT. Chapters cover general concepts, mechanisms of action, in vitro studies, pre-clinical animal studies, veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School, aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal), this book will appeal to anyone involved in the basic science, translational aspects and clinical applications of LLLT.

Contents:

What is Low-Level Laser (Light) Therapy?. History of Low-Level Laser (Light) Therapy. Lasers, LEDs, and Other Light Sources. Is Coherence Important in Photobiomodulation?. Tissue Optics. Light-Tissue Interaction and Light Dosimetry. Mitochondrial Light Absorption and Its Effect on ATP Production. Water as a Photoacceptor, Energy Transducer, and Rechargeable Electrolytic Bio-battery in Photobiomodulation. Role of Reactive Oxygen Species in Low-Level Laser Therapy. Molecular Basis for Photobiomodulation: Light-Induced Nitric Oxide Synthesis by Cytochrome c Oxidase in Low-Level Laser Therapy. Cytoprotective Effect of Low-Level Light Therapy using LEDs on Neurons. Low-Level Laser and Cultured Neural Tissue. Shining a Light on Parkinson's Disease. Low-Level Laser Therapy and Stem Cells. Antimicrobial Photodynamic Therapy. Low-Level Laser (Light) Therapy forWound Healing in Animal Models. Low-Level Laser Therapy for Arthritis in Animal Models: Beneficial Effect and Action Mechanism. Low-Level Laser Therapy for Lung Diseases: From the Bench to the Bed. Low-Level Laser (Light) Therapy in Tendon Healing in in Vitro and in Vivo Models. Bone Repair in Animal Models. Transcranial Low-Level Laser (Light) Therapy for Stroke and Traumatic Brain Injury in Animal Models. Phototherapy in Peripheral Nerve Repair and Muscle Preservation. Low-Level Laser Therapy for Spinal Cord Repair. Low-Level Laser (Light) Therapy for the Treatment of Visual System Injury and Disease. Protection from Cardiac Ischemia and Reperfusion Injury. Low-Level Laser and Experimental Aortic Aneurysm: Mechanisms and Therapeutic Implications. Low-Level Laser Therapy: A Treatment Modality for Multiple Sclerosis Targeting Autoimmunity and Oxidative Stress. Low-Level Laser Therapy as an Alternative Treatment for Snake Envenomation. Veterinary Low-Level Laser (Light) Therapy Applications for Companion Animals. Emergence of Low-Level Laser (Light) Therapy in Clinical Veterinary Practice. Photomedicine for Exotic Animals: A Case-Based Discussion. Recalcitrant Wound: Using Low-Level Laser (Light) Therapy to Manage Non-Healing Wounds and Ulcers. Clinical Applications with Low-Level Laser Therapy in Arthritis. Use of Low-Level Laser Therapy and Light-Emitting Diode Therapy to Improve Muscle Performance and Prevent Damage: From Animal Models to Clinical Trials. Low-Level Laser Therapy of Pain: Clinical Applications. Low-Level Laser Therapy and Its Application in Tinnitus. Laser Therapy for the Treatment of Radiculopathy. Difficult Path to Treating Acute Ischemic Stroke Patients with Transcranial Near-Infrared Laser Therapy. Low-Level Laser (Light) Therapy for Rehabilitation in Traumatic Brain Injury and Stroke, including Chronic Aphasia. Transcranial Near-Infrared Light for Major Depressive Disorder: Targeting the Brain Metabolism. Low-Level Laser Therapy: A Corner Stone in the Management of Cancer Therapy-Induced Mucositis. Photobiomodulation in Dentistry: Manipulating Biostimulation and Bioinhibition for Clinical Success. Photobiomodulation for the Clinical Treatment of Age-Related Macular Degeneration. Laser (Light) Therapy for Postherpetic Neuralgia. Laser Acupuncture. Intravascular Laser Irradiation of Blood. Nonsurgical Laser Therapy for Type 1 and Type 2 Diabetes. Laser Therapy of Traumatic Central Nervous System Injuries. Low-Level Laser (Light) Therapy: Aesthetic Applications for Hair. Low-Level Laser (Light) Therapy for Cosmetics and Dermatology. Low-Level Laser Therapy for Body Contouring and Fat Reduction. Transcranial Low-Level Laser (Light) Therapy for Neurocognitive Enhancement. Post-Operative Uses of Low-Level Laser Therapy. Bright New World: Future Directions of Low-Level Laser (Light) Therapy.